低强度电磁场对高胆固醇饮食兔血脂水平的影响  

Effects of Exposing Rabbits with Hypercholesterolemic Feed to Low Intensity Electromagnetic Fields on Levels of Blood Lipid

作　　者：申广浩[1] 罗二平[1] 路丽华[2] 吴小明[1] 汤池[1] 李雪琦[1] 

机构地区：[1]第四军医大学生物医学工程系军队卫生装备与计量学教研室,陕西西安710033 [2]第四军医大学基础部化学教研室,陕西西安710033

出　　处：《中国医学物理学杂志》2004年第4期244-245,共2页Chinese Journal of Medical Physics

基　　金：国家自然科学基金资助项目(50077023)

摘　　要：目的:为了探讨低强度电磁场对长期进食高胆固醇饲料兔血脂水平的影响。方法:本实验采用低强度脉冲电磁场进行随机对照实验研究,将24只雌性5月龄新西兰大耳白兔随机分为3组:对照组、磁场组和高脂组(n=8)。对照组用常规饲料喂养,磁场组和高脂组用高胆固醇饲料饲养,其中磁场组暴露于强度分别为10×10-4T的脉冲磁场下(f=15Hz),暴磁时间为10h/d。饲养8周后测定其血液中胆固醇、三酰甘油、高密度脂蛋白等指标。结果:与对照组比较,高脂组血脂水平的差异具有显著性意义(P<0.01)。与高脂组比较,磁场组胆固醇和三酰甘油均明显降低(P<0.01),而高密度脂蛋白升高显著(P<0.01)。结论:提示低强度脉冲电磁场能够显著改善血脂指标,对心血管疾病有良好的预防作用。Objective: To investigate the effects of exposing rabbits with hypercholesterolemic feed to low intensity electromagnetic fields(EMFs) on levels of blood lipid. Methods: By using 15 Hz pulsed low intensity EMFs (10×10-4 T), Examiner-blinded randomized controlled experiments were conducted. 24 female white big ear rabbits were randomly divided into three groups(control group, magnetic group and hyperlipid group). Control group was fed with normal diet and other groups were fed with hypercholesterolemic diet, thereinto. Magnetic group were fed in EMFs(10 h/d). After eight weeks, levels of blood lipid were examined, such as serum total cholesterol, triglyceride, high density lipoprotein (HDL), etc. Result: Compared with control group, the levels of blood lipid of hyperlipid group showed statistically significant differences (P <0.01). Compared with hyperlipid group, the serum total cholesterol and triglyceride values evidently decreased (P <0.01). On the contrary, HDL value obviously increased (P <0.01). Conclusion: Low intensity pulsed EMFs is effective in improving the levels of blood lipid. It is favorable to the prevention of cardiovascular diseases.

关 键 词：电磁场 血脂 高密度脂蛋白 

分 类 号：R312[医药卫生—基础医学]