铅对作业工人周围神经传导速度与生物学指标的影响  

Analysis of effects on conduction velocity of the peripheral nerve and biological indexes in workers exposed to lead

作　　者：朱玉华[1] 曹钟兴[1] 田月秋[1] 吴公孙[1] 李健[1] 周敏杰[2] 

机构地区：[1]上海第二医科大学新华医院职业病科,上海200092 [2]上海第二医科大学新华医院电生理科

出　　处：《上海第二医科大学学报》2004年第7期575-577,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：目的 探讨铅对周围神经传导速度和生物指标的影响。方法 66例接触者和40例对照者进行周围神经传导速度和各项生物指标的检测。结果 接触组中>10年工龄组和<10年工龄组分别与对照组周围神经传导速度比较有显著差异,其中正中神经、尺神经感觉传导速度(MCV、SCV)减慢、远端感觉潜伏期(sL)、腓肠神经SCV延长(P均<0.05)。接触组中>10年工龄组与<10年工龄组生物学指标PbB、ZPP、EFP、Hb、PbU比较有显著差别(P<0.05);周围神经传导速度、生物学指标异常率比较两组无显著差异(P>0.05),但相对危险度>10年工龄组分别是<10年工龄组的4.1和5.3倍。结论 提示长期接触铅对周围神经传导速度可产生不同程度的影响。Objective The aim is to study the effect on the conduction velocity of the peripheral nerve and biological indexes in workers exposed to lead. Methods In 66 observed subjects and 40 persons as the control group, the conduction velocity of peripheral nerve was examined by electromyography and several biological indexes were tested. Results The sense conduction velocity (MCV,SCV) of the median nerve and ulnar nerve was much slower and the distal sense latency( SL) of sural nerve was longer in > 10 years workers than in < 10 years controls (P < 0. 05). Biological indexes PbB ,ZPP,EFP, Hb and PbU were different between < 10 years and >0 years groups. The abnormal rate of the conduction velocity of the peripheral nerves and biological indexes in > 10 years group has no more significant difference than in < 10 years group, but the relative risk is 4. 1 and 5.3 times higher, respectively. Conclusion Lead is harmful to the peripheral nerve system in workers exposed for a long term.

关 键 词：铅 作业工人 周围神经 传导速度 生物学指标 神经毒作用 

分 类 号：R131[医药卫生—劳动卫生]