反复呼吸道感染对儿童胰岛素样生长因子-Ⅰ及免疫球蛋白水平的影响  

Serum level of IGF-1 and immunoglobulin in children with recurrent respiratory tract infection

作　　者：刘汝河[1] 黄宇戈[1] 肖红[1] 黄志敏[1] 揭育丽 

机构地区：[1]广东医学院附属医院儿科,广东湛江524001 [2]广东医学院附属医院同位素科

出　　处：《中国实验诊断学》2004年第4期344-345,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的　探讨血清GIF 1与免疫球蛋白在反复呼吸道感染 (RRTI)儿童发病中的关系。方法　对本院 2 0 0 3年5～ 10月份期间住院的 36例反复呼吸道感染儿童 (RRTI)血清IGF 1及免疫球蛋白IgG、IgA、IgM、IgE进行检测 ,并与同期体检的健康儿童 30例 (正常对照组 )进行比较。结果　RRTI组血清IGF 1、IgG、IgA含量较正常对照组降低 (P <0 0 5 ) ,RRTI组IGF 1与IgG、IgA水平变化呈正相关 (P <0 0 5 )。结论　免疫功能低下和IGFObjective To observe the level of IGF 1 and immunoglobulin(Ig) in children with recurrent respiratory tract infection(RRTI), to further investigate the relation of IGF 1 and Immunoglobulin(Ig) in children with RRTI. Methods Levels of IGF 1 and Immunoglobulin(Ig) were measured in 36 cases of children with RRTI from 2003.5 to 2003.10, and compared with those in the control group. Results In RRTI gruop, the levels of IgG, IgA and IGF 1 were lower than those of the control groups respectively( P <0 05). The level of IGF 1 was also significantly correlated with IgG, IgA(R=0 396, P <0 05; R=0 275, P <0 05). Conclusion The hypoimmunofunction and IGF 1 deficiency were important factors in RRTI pathogenesis.

关 键 词：儿童 反复呼吸道感染 胰岛素生长因子-1 免疫球蛋白 

分 类 号：R725.6[医药卫生—儿科]