泌尿生殖道非淋菌性感染及耐药性分析  

Study on nongonococcal infections and drug resistance to antibiotics of genitourinary tract

作　　者：刘君 张晓凤 

机构地区：[1]辽阳市第二医院检验科,辽阳111000 [2]辽阳市卫生局

出　　处：《中国实验诊断学》2004年第4期433-435,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的　比较不同性别患者标本中支原体和衣原体分离率及对 6种抗菌素的耐药性。方法　采用IST和VI DAS试剂盒 ,对 4 5 5例疑为NGU患者的泌尿生殖道标本进行了支原体和衣原体检测 ,同时对支原体检测阳性标本进行了菌落计数和抗生素敏感性检测。结果　 4 5 5例标本中支原体和衣原体分离率为 36 8% ,其中男性标本中支原体和衣原体分离率为 19 9% ,女性标本中支原体和衣原体分离率为 5 2 3%。Uu菌落计数结果 ,≥ 10 4 cfu ml比较女性(74 4 % )高于男性 (6 0 0 % ) ;Mh菌落计数结果 ,≥ 10 4 cfu ml比较女性 (35 8% )与男性 (36 4 % )基本相同。支原体对PRI保持敏感 ,对DOX、JOS、OFL、ERY、TET的耐药率女性和男性标本各不相同。结论　NGU患者中支原体和衣原体是主要的病原 ,监测支原体的耐药性对指导临床治疗具有重要意义 ,原始霉素 (PRI)和强力霉素 (DOX)Objective To compare the infectious rate of Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) and Chlamydia trachomatis(CT), and to analysis the drug rresistance to 6 antibiotics of Mh and Uu. Methods CT in genitourinary tract of 455 NGU patients was detected by kit of VIDAS. Uu and Mh in genitourinary tract was detected by kit of IST. Results In 455 tested samples, 36.8% were Mycoplasma and Chlamydia positive. In 216 virility tested samples, 19.9% were Mycoplasma and Chlamydia positive. In 239 female tested samples, 52.3% were Mycoplasma and Chlamydia positive. In 216 virility tested samples, 60^ were Uu≥10 4 cfu/ml, 36.4% were Mh≥10 4 cfu/ml; In 239 female tested samples, 74.4% were Uu≥10 4 cfu/ml, 35.8% were Mh≥10 4 cfu/ml. The sensitivity of Mycoplasma to those antimicrobials from high to low, was as follows:Pristinamycine, Doxycycline, Josamycin, Tetracycline, Ofloxacin, Erythromycin. Conclusion In genitourinary tract, Mycoplasma infections is taller than Chlamydia infections. Resistance monitoring of Mycoplasma periodically has important significance in clinical drug treatment.

关 键 词：泌尿生殖道 支原体感染 衣原体感染 耐药性 

分 类 号：R691.3[医药卫生—泌尿科学]