青年冠状动脉性心脏病患者冠状动脉病变特点及危险因素分析  

Pathologic changes of coronary artery and risk factors of coronary heart disease in young people

作　　者：李宗军[1] 王志[1] 

机构地区：[1]北京博爱医院急诊科,北京市100068

出　　处：《中国康复理论与实践》2004年第7期427-428,共2页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的探讨青年冠状动脉性心脏病 (CHD)患者的冠状动脉病变特点 ,分析危险因素的影响 ,为防治青年CHD提供依据。方法将经冠脉造影确诊的CHD患者 192例分为 2组 ,青年组 (≤ 40岁 ) 91例、中老年组 ( >40岁 ) 10 1例。分析两组患者的冠状动脉病变及CHD危险因素特点 ,并对危险因素做多元回归分析。结果青年组患者冠脉病变以单支病变为主 ,占 64 % ,狭窄程度均匀分布 ;中老年组患者冠脉病变多为多支病变 ,2支和 3支病变占 71% ,狭窄程度轻重分布不均匀。多元回归分析显示 ,CHD危险因素中的男性、吸烟、高脂血症、家族史和C反应蛋白 (CRP)升高与青年CHD高度相关 (均P <0 0 1)。结论青年CHD患者冠状动脉以单支病变为主 ,狭窄程度分布均匀 ,其主要危险因素是男性、吸烟、高脂血症、家族史和CRP。Objective To assess characteristics of coronary artery lesions and risk factors of coronary heart disease (CHD) in young people with coronary arteriography.Methods 192 patients with CHD diagnosed by coronary arteriography were divided into the young group (91 cases, 25—40 years old) and senile group (101 cases, 41—84 years old). Characteristics of coronary artery lesions and risk factors of CHD of two groups were analyzed, and risk factors were especially tested with logistic regression.Results Coronary artery lesions in the young group were characterized in most patients by singles vessel lesion (64%), while by multi vessels lesion (71%) in the senile group. Multiple logistic regression analysis showed that risk factors such as male, smoking, hyperlipemia, family history and increassed C reactive protein (CRP) were highly related with CHD( P <0 01). Conclusion Single vessel lesion is a feature of young patients with CHD, and independent and related risk factors of CHD in the young group are male, smoking, hyperlipemia, CHD family history and CRP.

关 键 词：冠状动脉疾病 冠状动脉造影 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]