经皮睾丸精子抽吸术治疗无精子症的研究  

Research on treatment azoospermia by percutaneous testicalar sperm aspiration.

作　　者：汪李虎[1] 吴敬之[1] 余云香[1] 易艳红[1] 张小庄[1] 

机构地区：[1]广东省妇幼保健院集爱遗传与不育诊疗中心,广州510010

出　　处：《中国优生与遗传杂志》2004年第4期120-121,132,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的　探讨经皮睾丸精子抽吸术 (PTSA)获取睾丸精子结合卵胞浆内单精子注射术 (ICSI)治疗梗阻性和非梗阻性无精子症 ,使之获得亲生子女。方法　对 12 1例因男性梗阻性及非梗阻性无精子症患者进行诊断性穿刺 ,均证实有精子后进行 119个周期PTSA +ICSI治疗。结果　共获卵子 15 14个 ,成熟卵 985个 ,胚胎 74 1个 ,平均每例 6 .2 3个胚胎 ,总受精率74 .4 % ,卵裂率 97.6 % ;共移植 114个周期和冷冻胚胎移植 5个周期 ,平均移植 2 .86个胚胎 ,B超证实临床妊娠 4 8例 ,临床妊娠率 4 0 .3%。结论　采用PTSA技术获取的睾丸精子进行ICSI是治疗梗阻性及非梗阻性无精子症的一种安全、简单、有效的方法。Objective: To investigate the effect of intracytoplasmic sperm injection (ICSI) combined with percutaneous testicular sperm aspiration(PTSA) in the treatment of severe male infertility such as obstructive azoospermia(OA) and non- obstructive azoospermia (NOA). Methods: After a total of 121 PTSA were performed for diagnostic purpose, 119 to obtain testicular sperm on the day of egg retrievol for couples have undergone ICSI. Results: 985 MⅡ oocytes from 1514 eggs were injected in 119 cycles, 741 fertilized, and all 114 embryo implanted (including 4 fronzen ET) , 48 couples achieved clinical pregnancy(clinical pregnancy rate 40.3%). Conclusions: PTSA combined with ICSI is an effective method for treatment of obstructive azoospermia and non- obstructive azoospermia.

关 键 词：睾丸精子 抽吸术 胞浆内单精子注射术 无精子症 

分 类 号：R698[医药卫生—泌尿科学]