超声波联合非甾体抗炎药治疗膝关节骨关节炎的临床效果  

Clinical Effectiveness of Ultrasound Wave Therapy Combined with Non-steroid Anti-inflammatory Drugs in the Treatment of Knee Osteoarthritis

作　　者：何成松[1] 李涛[1] 杨大鉴[1] 刘曦[1] 胥方元[1] 杨敏[1] 

机构地区：[1]泸州医学院附属医院康复医学科,四川泸州646000

出　　处：《中国康复》2004年第4期226-227,共2页Chinese Journal of Rehabilitation

摘　　要：目的 :对比研究超声波联合非甾体抗炎药 (NSAIDs)与传统NSAIDs治疗老年膝关节骨关节炎 (OA)的临床疗效。方法 :膝关节骨关节炎患者 132例 ,随机分为联合组、对照组 1和对照组 2各 4 4例。联合组给予环氧化酶 2 (COX 2 )抑制剂罗非昔布及超声波治疗 ,对照组 1和 2分别单独接受罗非昔布及超声波治疗 ,并比较 3组治疗后的临床效果。结果 :经 8周治疗后 ,平均Womac关节炎指数评分和平均OA严重程度指数改变程度 ,联合组均显著优于 2个对照组 (P <0 .0 5 )。结论 :通过 2种不同方法的联合治疗可使膝关节OA的临床效果得到进一步提高。Objective: To comparatively study the efficacy of ultrasound wave therapy combined with non steroid anti inflammatory drugs (NSAIDs) vs NSAIDs or ultrasound wave therapy alone in the treatment of knee osteoarthritis. Methods: Patients with knee osteoarthritis were randomized to 3 groups ( n =44 in each group) subject to ultrasound wave therapy combined with NSAIDs rofecoxib (experimental group), rofecoxib alone (control group A) or ultrasound wave alone (control group B) respectively. All patients were treated for 8 weeks. Results: At the end of the trial, the effective rate in the experimental group (54 %) was significantly higher than in the two control groups (21 % and 23 %, respectively). The experimental group was superior to two control groups in either Womac or osteoarthritis severity index. Conclusion: Ultrasound wave therapy in combination with NSAIDs is shown to be more effective than NSAIDs or Ultrasound wave therapy alone in treating knee osteoarthritis.

关 键 词：超声波 消炎药 非甾类 膝关节 骨关节炎 

分 类 号：R684.3[医药卫生—骨科学]