影响法洛四联症患者存活的因素  

Analysis of survival factor in the patients with tetralogy of Fallot

作　　者：朱鲜阳[1] 王淑范[1] 张玉威[1] 韩秀敏[1] 邓东安[1] 全薇[1] 盛晓棠[1] 王琦光[1] 金岩[1] 

机构地区：[1]解放军心血管内外科研究所

出　　处：《心脏杂志》2004年第4期359-361,共3页Chinese Heart Journal

摘　　要：目的 :分析影响法洛四联症患者存活的因素。方法 :对 2 134例法洛四联症患者的资料进行回顾性分析。根据住院时年龄分儿童组和成人组 ,成人组 (≥ 15岁 ) 4 6 0例 ,儿童组 (<15岁 ) 16 74例。通过症状、体征、X线胸片、心电图、超声心动图和心血管造影资料分析 ,观察其临床表现特点。结果 :经统计学处理发现低氧发作、右室流出道狭窄的严重程度、左心室发育不良和并存的其它心脏畸形的发生率 ,儿童组显著高于成人组 (P<0 .0 1) ,而肺动脉瓣下室缺的发生率 ,成人组则显著高于儿童组 (P<0 .0 1)。结论 :低氧发作 ,右室流出道狭窄的范围及程度 ,室缺位置 ,左室大小和并存畸形是影响法洛四联症患者存活的主要因素。AIM: To assess the clinical manifestation and survival factors in the patients with tetralogy of Fallot. METHODS: 2134 patients were reviewed retrospectively. They were divided into two groups based on the admission ages:one consisting of 460 adults aged ≥15 years old and the other,1674 children aged <15 years old. The symptoms, physical signs, chest X rays, electrocardiograms, echocardiograms, and the cardioangiography features were analyzed and compared between the children and the adults. RESULTS: The incidences of the hypoxia spells, the severity degree of right ventricular outflow obstruction, the left ventricle dysplasia and other malformation accompanied were more markedly increased in the children than in the adults (P<0 01). The incidence of ventricular septal defects of infra pulmonary valve in the adults was significantly higher than that in the children(P<0.01). CONCLUSION: The hypoxia spells, the ranges and degree of right ventricular outflow obstruction, the position of ventricular septal defects,the left ventricular dimension and the accompanied malformation were main influence factors in the survival of patients with Tetralogy of Fallot.

关 键 词：法洛四联症 儿童 成人 存活因素 

分 类 号：R541.1[医药卫生—心血管疾病]