妊娠肝内胆汁淤积症病因及对母婴危害的研究  

A study on pathogenesis and maternal and fetal risks of ICP

作　　者：冯丽霞[1] 胡珊[1] 李力[1] 

机构地区：[1]第三军医大学大坪医院野战外科研究所妇产科,重庆400042

出　　处：《国外医学（妇幼保健分册）》2004年第4期223-226,共4页Foreign Medical Sciences (Section of Maternal and Child Health)

摘　　要：妊娠肝内胆汁淤积症是妊娠期特有的一种疾病。妊娠胆汁淤积症病因目前不是很清楚 ,大量研究认为与雌、孕激素代谢 ,环境因素、遗传因素及病毒性肝炎有一定关系。其对母婴均有不良影响 ,尤其对围生儿危害更大 ,可导致早产、胎儿窘迫、死胎、死产率增高等一系列产科并发症。Intrahepatic cholestasis of pregnancy(ICP) is a pregnancy-specific disorder. The pathogenesis of ICP is unclear at present. A lot of researches suggested that it may be related to the metabolism of estrogen and progesterone, environmental factors , hereditary factors and viral hepatitis. ICP do harm to both mother and fetus, especially to the perinatal neonates, and induces higher frequency of preterm labor, fetal distress, unexplained fetal death and stillbirth.

关 键 词：妊娠 肝内胆汁淤积症 病因 母婴危害 

分 类 号：R714.25[医药卫生—妇产科学]