高原康胶囊对快速进入高原者水负荷的影响及意义  

The Effects of Gaoyuankang Capsule on Water Load of Entrants Landing at High Altitude Rapidly

作　　者：李素芝[1] 郑必海[1] 王洪斌[1] 李尚师[1] 周小波[1] 姚文新[1] 邓勇[1] 

机构地区：[1]西藏军区总医院全军高山病防治研究中心,西藏拉萨850007

出　　处：《中国医师杂志》2004年第9期1197-1199,共3页Journal of Chinese Physician

摘　　要：目的　通过实验了解高原康胶胶对大批快速进入高原者水负荷的影响及其意义。方法　将 80名由平原乘飞机初次进入高原的战士随机分为实验组和对照组 ,实验组于平原登机前开始给予口服高原康胶囊 ,2粒 /次 ,3次 /d ;对照组不给予任何药物预防 ,在两组进入高原的前 1d及进入高原的第 3d下午后给予水负荷实验 ,并对其饮水后 15 0min内各时相点的尿量进入观察比较。结果　对照组进入高原后水负荷实验 61～ 15 0min各时间段的尿量及相应时间的总尿量与平原时相应各时间段的尿量及相应时间的总尿量相比显著减少 (P <0 0 5～ 0 0 1) ,实验组则无显著变化 ;且实验组进入高原后水负荷实验 60～ 90min的尿量及 12 0、15 0min的尿量显著多于对照组 ( P <0 0 5 )。结论　高原康能改善机体高原缺氧状态下水负荷的调节能力 。ObjectiveTo explore the influence of Gaoyu ankang capsule on the water load of ent rants landing at high altitude rapidly and its significance. Methods 80 soldiers who went from plain to high altitude by air for the first time were randomly divided into, experi mental group and control g roup. Experimental group was asked to orally take 2 granules of Gaoyuankang capsule 3 times per day for 3 days before boarding a plane. Control group was not given any pharmaco-prevention. Water load experiment was performed at the fi rst day before and at the third day after landing at high altitude in the tw o groups. Urine quantity of two groups was recorded and compared at various time points in 150 minutes after water was given. Results Urine quantity at each time points in 61～150 minutes after water load experiment beginning and total urine quantity i n corresponding time points remarkably de creased in the control group after landing at high altitude(P<0 05～0 01) , but there was not distinct difference in the above two indices in the expreime n tal group. Urine quantity in 61 to 90 minutes and total urine quan tity in 120, 150 minutes after water load experiment beginning in the experiment ed group were significantly more than those in the control gro up(P<0 05) ConclusionGaoyuankang capsule could improve body capabil it y of regulating water load in hypoxemia status at high altitude, and had active prevention effect to acute high altitude diseases.

关 键 词：高原康胶囊 高原 水负荷 急性高原病 

分 类 号：R594.3[医药卫生—内科学]