胫骨定量超声测量及临床应用探讨  

Quantitative ultrasound measurement of tibia and clinical application

作　　者：伍贤平[1] 周智广[1] 周继凯[1] 伍汉文[1] 

机构地区：[1]湖南医科大学代谢内分泌研究所附二医院内分泌科

出　　处：《中国骨质疏松杂志》1997年第1期43-45,共3页Chinese Journal of Osteoporosis

摘　　要：用ＳｏｕｎｄＳｃａｎ２０００骨定量超声（ＱＵＳ）仪测量胫骨超声速度（ＳＯＳ），同时与单光子吸收法（ＳＰＡ）测量前臂１／３处骨矿密度（ＢＭＤ）比较。两方法测得２０８例患者和健康志愿者结果相关（ｒ＝０．６７８，Ｐ＜０．００１）。４２例健康绝经妇女ＳＯＳ和ＢＭＤ与绝经时间呈负相关（ｒ＝－０．４１７和－０．４７９，Ｐ＜０．０１），７３例＞４０岁的健康志愿者ＳＯＳ和ＢＭＤ与年龄呈负相关（ｒ＝－０．２９３和－０．３７３，Ｐ＜０．０５）。与性别和年龄相匹配的正常参考值比较，结果＜ｘ－２ｓ者ＱＵＳ检出３４例，占１６．３％；ＳＰＡ２３例，占１１．０％，ＱＵＳ的诊断敏感度约是ＳＰＡ的１．５倍。We have assessed a new method of quantitative ultrasound (QUS,with SoundScan 2000 of Myriad Ultrasound Systems Ltd)for measuring the speed of sound(SOS,m s-1) and diagnosis of osteoporosis in the conical bone of the right tibial shaft. The QUS was compared with single photon absorptiometry(SPA) for measuring the bone mineral density (BMD, g cm-2) at the forearm (1/3 site).SOS significantly correlated with BMD (r= 0. 678, P<0. 001 ) in 208 subjects, including patients with various metabolic bone diseases and 99 healthy volunteers by QUS and SPA. The QUS was most reproducible with intra- and intercoefficients of 0. 22% and 0. 39% respectively. In the healthy late postmenopausal women,there was a correlation of SOS and BMD with years since menopause (r =-0. 417 and -0. 479,P<0. 01 and 0. 002). In the healthy volunteers aged over 40 years,there was also a correlation of SOS and BMD with age(r=-0. 293 and -0. 373,P<0. 05 and 0. 01 ). Compared with healthy subjects matched by sex and age,34 cases by QUS and 23 cases by SPA were were detected to have the values lower than x-2S of healthy subjects,the diagnostic sensitivity of QUS to SPA being about 1. 5 times. The results show that the technique of QUS is highly sensitive and precise. The diagnosis of osteoporosis and prediction of osteoporotic fracture by QUS are satisfactory.

关 键 词：胫骨 定量超声 超声测量 骨质疏松 单光子吸收法 

分 类 号：R681[医药卫生—骨科学]