100Hz正弦波振动对悬吊大鼠比目鱼肌肌梭传入放电的影响  

Influence of 100 Hz Sinusoidal Vibration on Muscle Spindle Afferents of Soleus Muscles in Suspended Situation Rat.

作　　者：任俊蝉[1] 樊小力[1] 宋新艾[1] 李强[1] 

机构地区：[1]西安交通大学医学院生理学教研室

出　　处：《航天医学与医学工程》2004年第5期340-344,共5页Space Medicine & Medical Engineering

基　　金：国家自然科学基金资助 ( 3 90 70 3 3 4)

摘　　要：目的探讨 1 0 0Hz正弦波振动对尾部悬吊大鼠比目鱼肌肌梭传入放电的影响。方法采用尾部悬吊大鼠模型模拟失重 ,用振动仪实施 1 0 0Hz正弦波刺激 ,利用从背根分离神经细束并记录比目鱼肌肌梭传入放电的方法 ,7d后观察大鼠比目鱼肌肌梭传入放电的变化。结果 1 )吊尾 7d后 ,大鼠比目鱼肌肌梭的传入放电与对照组相比明显减低 (P <0 .0 5 )。 2 )吊尾加 1 0 0Hz正弦波振动 7d后 ,与单纯吊尾组相比肌梭的传入放电明显增多 (P <0 .0 5 )。结论 1 0 0Hz正弦波振动可选择性兴奋肌梭 。Objective To study influence of 100 Hz sinusoidal vibration on muscle spindle afferents discharges of rat soleus muscles in simulated-weightlessness situation. Method The tail-suspended rat model was used to simulate weightlessness, and 100 Hz sinusoidal vibration was performed by a vibrator. Unit activity was recorded electrophysiologically from the centrally cut filaments of the spinal dorsal roots innervating muscle spindles of the rat soleus muscle; then observation on the changes in afferent discharges from muscle spindles in rat soleus muscles were made after 7 d. Result 1)Compared with control muscle spindle afferents discharges of rat soleus muscles decreased after 7 d tail-suspension(P<0.05).2) Compared with suspension the afferent discharges from soleus muscle spindles increased after 7 d tail-suspension with 100 Hz sinusoidal vibration. Conclusion Sinusoidal vibration(100 Hz; 300 μm) can selectively activate muscle spindles . Muscle spindle afferent input of the suspended rats increased after the application of 7 d 100 Hz sinusoidal vibration.

关 键 词：尾吊 正弦波振动 比目鱼肌 肌梭 传入放电 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]