211种贵州民族中草药抑制HBsAg的体外实验研究  

An experimental investigation on 211 Chinese medicinal herbs against HBsAg in Guizhou province

作　　者：舒莉萍[1] 左丽[1] 李永念[1] 陈阿英[1] 杨小生 

机构地区：[1]贵阳医学院免疫学教研室,550004 [2]贵州省中国科学院天然产物化学重点实验室,贵阳550006

出　　处：《贵州医药》2004年第8期701-702,共2页Guizhou Medical Journal

基　　金：贵州省中药现代化科技生产研究开发专项重大课题资助项目 (黔科合中药专字 [2 0 0 3 ] 0 7)

摘　　要：目的筛选贵州民族中草药对HBsAg的作用。方法选取 2 11种贵州省民族中草药提取物分别与HBsAg 37℃作用 1小时 ,通过ELISA双抗体夹心法分别检测HBsAg与药物作用前后的含量 ,计算HBsAg经药物作用后下降的百分率 ,筛选出有效的药物。结果 2 11种药物中筛选出 2 4种药物有抗HBsAg作用 ,占总数的 11 4 %。结论贵州民族中草药中有部分药物对HBsAg的抑制作用。Objective To assess the effects of Chinese medicinal herbs from Guizhou province against HBsAg. Methods 211 extracts of Chinese medicinal herbs from Guizhou province were exposure 1h with HBsAg in vitro, respectively. The concentrations of HBsAg were assessed with Sandwich ELISA. The declination percent of HBsAg was calculated.Results 24 kinds of herbs (11.4%) have against HBsAg effectively. Conclusion The results indicated that some Chinese medicinal herbs from Guizhou province have effect to inhibit HBsAg.

关 键 词：贵州 民族中草药 抑制作用 HBSAG 体外实验 酶联免疫吸附试验 抗原 

分 类 号：R512.62[医药卫生—内科学]