家族性与散发性预激综合征临床及电生理比较  

The Comparison of Familial and Sporadic Preexcitation Syndrome in Clinical and Electrophysiology

作　　者：刘文玲[1] 胡大一[1] 刘国树[2] 单兆亮[2] 刘德强[3] 王玉堂[2] 

机构地区：[1]北京大学人民医院心内科,北京100044 [2]解放军总医院,北京100850 [3]邯郸市第一医院,邯郸056000

出　　处：《中国医药导刊》2004年第4期239-241,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:了解家族性预激综合征的临床及电生理特点。方法:总结了家族性预激综合征30例,散发性预激综合征363例,对两组患者的临床及电生理特点进行了比较。结果:家族性预激综合征发病率占预激综合征患者的7.6％。家族性患者多旁道者为20％,散发患者为5％,P=0.001。其它临床及电生理特点两组均无显著性差异。结论:家族性预激综合征临床及电生理表现与散发性预激综合征基本相似,但多旁路者较散发患者多见。Objective: The objective is to find the prevalence of familial preexcitation syndrome and the clinical and electrophysio-logic characteristics of the disease. Methods: 30 cases of familial preexcitation syndrome and 363 cases of sporadic patients were compared in clinical and electrophysiologic characteristics. Results: The prevalence of familial preexcitation syndrome was 7.6% of all of the preexcitation syndrome. The frequency of multiple accessory pathways in familial cases (20%) was much higher than that of sporadic cases(5%), P = 0.001 .The majority of the accessory pathways located at lateral of left ventricle in both groups, 56.7% vs 54.5% ,there no marked differences in the two groups.The prevalence of anterograde preexcitation in familial cases and in sporsadic cases were 35.7% vs 40.4%;and that of retrograde preexcitation were 45.2% vs 46.3%;The prevalence of intermittent preexcitation in familial cases and in sporsadic cases were 4.8% vs5.9% in sporadic cases; there were no marked differences in two groups. Conclusion: The prevalence of familial preexcitation syndrome was 7.6% of all of the preexcitation syndrome. The characteristics of electrophysiology , age, and sex of the familial preexcitation were in the same as that of sporadic preexcitation.But the prevalence of multiple accessory pathways was much higher in familial preexcitation, which vulnerable occurred ventricular fibrilation and resulted in sudden death.Thereby,a detail family history should be obtained from all patients with preexcitation syndrome. A more aggressive diagnostic approach in relatives with suggestive symptoms appears to be warranted.

关 键 词：家族性预激综合征 散发性预激综合征 电生理 诊断 

分 类 号：R541.7[医药卫生—心血管疾病]