禽类养殖场人员禽流感病毒抗体水平调查  

Serological surveillance on antibody to avian influenza subtype H5,H9 virus in poultry breeding workers

作　　者：孙虹[1] 马洪波[2] 杨卫路[3] 鲁恩洁[3] 叶立青[2] 陈琨[2] 赖子平[2] 王岩[2] 

机构地区：[1]第一军医大学流行病学教研室,广州510515 [2]珠海出入境检验检疫局 [3]广州市疾病预防控制中心

出　　处：《中国公共卫生》2004年第8期989-990,共2页Chinese Journal of Public Health

摘　　要：目的　调查珠海地区养殖场人员中禽流感H5和H9二种亚型血清中抗体水平 ,以了解上述 2种禽类甲型流感病毒亚型以往的接触感染情况 ,为防治人间禽流感提供科学依据。方法　珠海地区养殖场人员血清 2 77份 ,正常出入境人员血清 2 70份 ,通过血凝抑制试验HI实验进行抗体检测。结果　养殖场人群中H9亚型抗体阳性率为2 17% ,同时发现有 1份血清H5抗体阳性 ,H5抗体阳性率为 0 36 %。而正常出入境人群H9亚型抗体阳性率为2 96 % ;未见H5亚型抗体的存在。结论　H9亚型在养殖场人群和出入境人群中的存在隐性感染 ,但感染率不高 ;养殖场人群H5亚型抗体的存在也应值得注意。Objective To detect the seroepidemiologic antibody to the subtypes of avian influenza A virus,H5 and H9 in poultry breeding workers,to understand the infection of avian influenza A virus.Methods For detecting antibody to these two subtypes with HI test,277 serum specimens were collected from poultry breeding workers,and 270 were from normal Entry-Exit passengers in Zhuhai port.Results In poultry breeding workers,the positive rate to H9 was 2 17%,and 1 serum specimens had antibody to H5,The positive rate was 0 36%,while in normal Entry-Exit passengers,the positive rate to H9 was 2 196%,but none had antibody to H5.Conclusion H9 subtype influenza A virus had already infected human beings,the positive rate was not high.It was attention to H5 subtype in poultry breeding workers.

关 键 词：禽流感病毒 H5 H9 养殖场 

分 类 号：R511.7[医药卫生—内科学]