蛭丹化瘀中药配方颗粒冲剂与饮片煎剂体外抗RSV作用比较  

In vitro inhibition of respiratory syncytial virus with different forms of the prescriptions of traditional Chinese medicine zhidanhuayu

作　　者：刘玉华[1] 叶会初[1] 黄敏君[2] 

机构地区：[1]首都医科大学附属北京友谊医院儿科,北京100050 [2]北京热带医学研究所,北京100050

出　　处：《临床和实验医学杂志》2004年第3期152-153,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的　了解蛭丹化瘀中药配方颗粒冲剂与饮片煎成的蛭丹化瘀口服液在体外抑制呼吸道合胞病毒(RSV)作用是否相同。方法　观察RSV在两种制剂、不同药物浓度下对HEp -2细胞的致病作用。结果　蛭丹化瘀中药配方颗粒冲剂完全抑制RSV复制的最小浓度为 2 75mg/ml ;中药饮片煎成的蛭丹化瘀口服液完全抑制RSV复制的最小浓度为 2 75mg/ml。结论　两种制剂在体外抑制RSV复制作用强度相同 ,中药配方颗粒在加工过程中未改变药物的药性。Objective To study the in vitro antiviral effect of different forms of prescriptions of traditional Chinese medicine zhidanhuayu on respiratory syncytial virus (RSV) Methods Cytopathic effects(CEP)of RSV on Hep-2 cells were observed after adding different concentrations of solution prescription and boiling prescription of zhidanhuayu respectively Results The minimum concertration of both solution prescription and boiling prescription of zhidanhuayu for complete inhibition of CEP caused by RSV was 2 75 mg/ml Conclusion Both forms of prescriptions of traditional Chinese medicine zhidanhuayu showed in vitro anti-RSV effect

关 键 词：中药配方颗粒 蛭丹化瘀口服液 呼吸道合胞病毒 

分 类 号：R285[医药卫生—中药学]