SPECT脑灌注显像在脑出血急性期的临床研究  

Cerebral Perfusion with SPECT in Acute Intacerebral Hemorrhage

作　　者：牛争平[1] 聂永慧[2] 侯玉立[1] 李险峰[1] 

机构地区：[1]山西医科大学第一医院 [2]中国人民解放军总医院

出　　处：《中西医结合心脑血管病杂志》2004年第10期573-574,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：山西省教育委员会科技项目 (No .990 0 6)

摘　　要：目的　了解脑出血急性期脑灌注特点 ,为寻求新的治疗途径提供科学依据。方法　对 3 5例脑出血后 3d～ 5d的病人行单光子发射计算机断层扫描 (SPECT) ,并对发病初的神经功能缺损及发病后 2 8d的日常生活能力 (BI)评分。结果　脑血流量 (rCBF)与出血量及出血部位有关 :出血量越大 ,rCBF下降越明显 ;出血早期部分病人双侧大脑半球血流量均显著降低 ;SPECT评分与临床神经功能缺损评分呈直线相关 (r =0 .85 ,P <0 .0 1) ,与 2 8d时的BI评分呈直线负相关(r =-0 .81,P <0 .0 1)。结论　脑出血急性期存在缺血半暗带 。Objective To Acquire the features of cerebral perfusion in acute intracerebral hemorrhage (ICH)so as to provide scientific evidences for new therapeutic ways.Methods 35patients were examined with SPECT after 3～5 days of intacerebral hemorrhage;Early neurological impairment and daily life ability (BI) after 28 days were graded.Results The cerebral blood flow (rCBF)is related to both bleeding amount and bleeding positions;The more bleeding amount, the lower in rCBF;Obviously SPECT score has positive correlation with score of clinical neurological impairment (r=0.85,P<0.01)and has negative correlation with BI score after 28 days (r=-0.81,P<0.01).Conclusion There is ischemic penumbra in acute period of ICH. The reversion of ischemic penumbra is directly related to the patients’daily life abilities.

关 键 词：SPECT 脑灌注显像 脑出血 急性期 临床研究 

分 类 号：R817.4[医药卫生—影像医学与核医学]