人工肝支持系统治疗重型肝炎的效价比研究  

Research of effect and price relation in severe hepatitis treated by artificial liver support system

作　　者：李聪智[1] 谭德明[1] 候周华[1] 杨永峰[1] 罗向群[1] 龙云铸[1] 

机构地区：[1]中南大学湘雅医院传染科,长沙410008

出　　处：《中国血液净化》2004年第9期501-502,共2页Chinese Journal of Blood Purification

摘　　要：目的　对人工肝支持系统在治疗重型肝炎进行了疗效与价格关系的研究 ,旨在进一步了解人工肝支持系统在治疗重型肝炎中的价值。方法　将 82例患者分为治疗组和对照组 ,治疗组采用基础疗法 +人工肝支持系统 (血浆置换 +血液吸附 ) ,对照组采用基础疗法 ,两组按患者的PTA不同 (30 %～4 0 %、2 0 %～ 2 9%、<2 0 % )分为三组进行对比研究 ,观察患者的治愈好转率、平均住院日和平均费用。结果　PTA在 30 %～ 4 0 %和 2 0 %～ 2 9%的组中 ,人工肝治疗组的治愈好转率显著高于对照组 (P <0 .0 5 ) ,而住院天数明显少于对照组 (P <0 .0 5 ) ,但治疗费用与对照组比较无显著差异 (P >0 .0 5 )。PTA在 2 0 %以下的组中 ,人工肝治疗组在治愈好转率和平均住院日与对照组比较无显著性差异 (P >0 .0 5 ) ,但治疗费用较对照组高 (P <0 .0 5 )。结论　人工肝支持系统在治疗早、中期重型肝炎效果较好 ,具有很好的效价比关系 ,对该类患者应强调及时给予人工肝治疗 ,而对于晚期重型肝炎 ,人工肝支持系统与对照组在治愈好转率、平均住院日及治疗费用方面比较其效价关系不合理 。Objective To investing at the effect and price relation in severe hepatitis treated by artificial liver support system. Methods the 82 patients were divided into two groups, the severe hepatitis group in which the patients were treated by artifical liver support system (plasma exchange adsorption) plus generalization treatment and the control in which the pattents were treated by generalization treatment. Effective rate, hospitalization time and medial cost were observed. Results In the patients whose PTA ranged from 20% to 40%, the effective rate of artificial liver support system group was significantly higher than control group (P<0.05). The hospitalization time was significantly shorter than control group (P<0.05). There was no significant difference of medical cost between the two groups. The mediacal cost of the patients whose PTA lower than 20% was higher than contol group (P<0.05). Yet there were no significant difference of effective rate and hospitalization time between the two groups (P>0.05). Conclusion Artificial liver support system is effective to severe hepatitis in early stage.

关 键 词：人工肝支持系统 重型肝炎 治疗价值 

分 类 号：R318.14[医药卫生—生物医学工程]