超脉冲CO_2激光结合自体表皮移植治疗白癜风  

Combined Therapy of Ultrapulse CO_2 Laser with Autologous Epidermal Grafting in Vitiligo

作　　者：余文林[1] 刘春利[1] 曾海玲[1] 曾东[1] 

机构地区：[1]广州军区广州总医院激光整形美容中心,510010

出　　处：《中华皮肤科杂志》2003年第9期493-495,共3页Chinese Journal of Dermatology

摘　　要：目的探讨CO2激光结合自体表皮移植治疗白癜风的临床疗效。方法对1605例白癜风患者进行自体表皮移植治疗,共植皮30660片,其中局限型782例12151片,节段型319例8221片,泛发型226例7376片,散发型278例2912片。采用发疱取皮法,受皮区采用CO2激光汽化创面形成,治疗8周后判断疗效。结果治愈率79.04%,有效率13.17%,总有效率92.21%。以局限型和散发型效果最好,泛发型效果较差,身体各部以面部效果最佳,胸背部次之,眉区及发际最差。结论超脉冲CO2激光辅助自体表皮移植治疗白癜风具有操作简单、方便,手术时间短,出血少,皮片易存活,治愈率高的优点,值得临床推广。Objective To observe the clinical efficacy and safety of ultrapulse CO 2 laser-assisted au-tologous epidermal grafting for the treatment of vitiligo.Methods1605patients with30660skin grafts were treated by CO 2 laser-assisted autologous epidermal grafting.Among them,782patients had localized vi-tiligo,319segmental,226general and278scattered.Epidermal grafts were harvested with negative pressure blistering method from normally pigmented skin,and recipient areas were prepared with a ultrapulse CO 2 laser.The curative effect was evaluated8weeks later.Results79.04%of the lesions were cured complete-ly,and total response rate was92.21%,with better effect in localized and scattered lesions than in other le-sions.The best results were shown in face,while the worst results shown in brow and hairline lesions.Con-clusions The advantage of combined therapy of CO 2 laser with autologous epidermal grafting in vitiligo is of easy performance,convenience,high response rate,which is worthy of large scale application.

关 键 词：白癜风 自体表皮移植 超脉冲二氧化碳激光 发疱取皮法 

分 类 号：R758.41[医药卫生—皮肤病学与性病学] R622.1[医药卫生—临床医学]