球后放疗在甲状腺相关眼病治疗中的应用  

Therapeutic effect of retro-orbital radiation in thyroid-associated ophthalmopathy

作　　者：洪俊[1] 骆荣江[1] 严励[2] 刘宜敏[3] 廖文雄[1] 陈黎红[2] 

机构地区：[1]中山大学附属第二医院眼科,广州510120 [2]中山大学附属第二医院内分泌科,广州510120 [3]中山大学附属第二医院放疗科,广州510120

出　　处：《临床眼科杂志》2004年第4期333-334,共2页Journal of Clinical Ophthalmology

摘　　要：目的　探讨球后放疗在甲状腺相关眼病治疗中的作用。方法　对 2 0例 (4 0只眼 )甲状腺相关眼病的患者进行球后放射治疗 ,对治疗前后的眼球突出度、眼外肌横径值、球后浸润程度进行对比分析。结果　 2 0例 (4 0只眼 )甲状腺相关眼病患者球后放射治疗结束后的眼球突出度、眼外肌横径值、球后浸润程度均比治疗前明显改善(P <0 .0 1 ) ,眼病的刺激症状明显好转 ,治疗总有效率 70 .8% ,随访 8～ 1 8个月无并发症及后遗症发生。结论　利用直线加速器作球后放射治疗甲状腺相关眼病是一种副作用少、安全。Objective To explore the therapeutic effect of retro orbital radiation for thyroid associated ophthalmopathy Method 20 cases(40 eyes)with thyroid associated ophthalmopathy were performed retro orbital radiation therapy by using linear accelerator. The degree of proptosis , the transverse diameter of extraocular muscles and the degree of retro orbital infiltration were measured before and after radiation therapy, and compared respectively.Result In comparing their degree of eye proptosis , transverse diameter of extraocular muscles and the degree of retro orbital infiltration before and after radiation therapy , ophthalmopathy in 20 cases(40 eyes) were all alleviated after radiation therapy.(P<0.01),the irritation were released obviously. The effective rate was 70.8%.No complication and sequelea were found during 8 18 months follow up. Conclusion Retro orbital radiation by using linear accelerator proved to be a safe and effective way with less side-effect for thyroid-associated ophthalmopathy.

关 键 词：球后放疗 甲状腺相关眼病 治疗 临床应用 

分 类 号：R581[医药卫生—内分泌] R771.3[医药卫生—内科学]