D-核糖对激素诱发大鼠心肌缺血和心律失常保护作用的研究  

The protective role of D-ribose on myocardial ischemia and arrhythmia cordis induced by some hormone in rats.

作　　者：周升[1] 符史干[1] 许闽广[1] 高凌峰[1] 

机构地区：[1]海南医学院化学分析实验室,海南海口571101

出　　处：《中国热带医学》2004年第4期543-544,611,共3页China Tropical Medicine

基　　金：海南省教育厅高等院校科研资助项目 (No Hjkj 2 0 0 1 1 2 )

摘　　要：目的　观察D -核糖对一些激素诱发急性心肌缺血和心律失常的保护作用。　方法　从大鼠尾静脉注射D -核糖后分别给以抗利尿激素和肾上腺素 ,观察心电图T波幅度变化的时间、心电图心律失常开始时间和心跳停止时间。　结果　D -核糖能明显削弱抗利尿激素对T波的影响和延缓肾上腺素诱发心律失常的时间。　结论　DObjective To study the protective effects of D-ribose on acute myocardial ischemia and arrhythmia cordis caused by antidiuretic hormone and adrenaline in rats. Method To inject proper concentrations of D-ribose into the rats through their tail vein, separately give antidiuretic hormone and adrenaline, observe the changes in T waves on the electrocardiogram, and then study the beginning time of cardiac dysfunction and the terminal time of heartbeats. Results D-ribose could reduce the changes in T waves caused by antidiuvetic hormone. D-ribose could retard the starting time and prolong the life of the rats caused by adrenaline. Conclusion D-ribose has a protective role on acute myocardial ischemia and arrhythmia cordis induced by antidiuretic hormone and adrenaline in rats.

关 键 词：D-核糖 大鼠 心肌缺血 心律失常 心电图 T波幅度 激素诱发 

分 类 号：R542.2[医药卫生—心血管疾病] R541.7[医药卫生—内科学]