人芽囊原虫感染致慢性腹泻18例临床分析  

Analysis of 18 chronic diarrhea patients due to infection with Blastocystis hominis.

作　　者：徐凤全[1] 林玲[2] 李军[2] 时发茂[1] 

机构地区：[1]山东省寄生虫病防治研究所,山东济宁272000 [2]济宁市中区人民医院,山东济宁272000

出　　处：《中国热带医学》2004年第4期559-560,共2页China Tropical Medicine

摘　　要：目的　分析人芽囊原虫感染致慢性腹泻病人临床资料 ,评价人芽囊原虫病的临床诊断及治疗效果。　方法　诊断用直接涂片法检查病人粪便中的人芽囊原虫包囊 ;治疗用甲硝唑 ,成人 2 5 0～ 40 0mg/次 ,3次 /d ,7d为一疗程。　结果　 18例慢性腹泻病人病程为 3～ 2 4个月 ,粪便中均查到人芽囊原虫包囊 (包括阿米巴型、空泡型和颗粒型 ) ;用甲硝唑治疗的治愈率 1个疗程为 3 8 89% ,2个疗程为 10 0 %。　结论　粪便直接涂片镜检原虫包囊是确诊人芽囊原虫感染的有效方法 ,用甲硝唑治疗人芽囊原虫感染所致的慢性腹泻疗效显著。Objective To review clinical data concerning treatment of chronic diarrhea due to infection with Blastocystis hominis and evaluate the effectiveness of diagnosis and treatment of patients with Blastocystis hominis. Methods Fresh stool was collected from patients and Blastocystis hominis cysts were detected by microscopy examination of stool smears. The patients diagnosed were treated with metronidaole at the dose of 250mg～400mg/time, three times a day for a course of seven days. Results The average duration of infection of the patients was 9 months (3～24 months) and Blastocystis hominis cysts were detected from stool. The cure rates were 38.89% and 100% after treated with metronidazole in one course and two courses, respectively. Conclusion Detection of Blastocystis hominis from stool smears are effective for diagnosis of infection with Blastocystis hominis. Excellent therapeutic effectiveness can be achieved in treatment of patients with Blastocystis hominis by using metronidazole.

关 键 词：人芽囊原虫感染 慢性腹泻 甲硝唑 涂片镜检 粪便镜检 

分 类 号：R531[医药卫生—内科学] R442.2[医药卫生—临床医学]