乙酰唑胺和高原维康片对高原人体运动血乳酸及血氨的影响  

Effects of Acetazolamide and Vitamin Tablets on Human Blood Ammonia and Lactic Acid after Exercises at High Altitude

作　　者：崔建华[1] 张西洲[1] 战祥总[1] 张芳[1] 邢国祥[1] 马勇[1] 王伟[1] 李彬[1] 

机构地区：[1]解放军第18医院,新疆叶城844900

出　　处：《临床军医杂志》2004年第5期1-3,共3页Clinical Journal of Medical Officers

基　　金：军队"十五"医药卫生科研基金资助项目 (LXH 0 1 0 6)

摘　　要：目的　探讨乙酰唑胺、高原维康片和红牛饮料对高原人体运动时血乳酸 (BLA)及血氨 (Ammo)的影响。方法　对进驻海拔 3 70 0m高原半年的 40名健康青年随机分为乙酰唑胺组、高原维康片组、红牛饮料组及对照组 ,每组 10名。在安静时、服药前、服药第 10天及停药第 10天分别采用功率自行车进行渐增负荷运动至力竭 ,测定其血清中BLA和Ammo含量。结果　 ( 1)高原力竭运动使BLA和Ammo增加 (P <0 .0 1) ;( 2 )给予乙酰唑胺、高原维康片和红牛饮料 10d即可使BLA ,Ammo降低 (P <0 .0 1或P <0 .0 5 )。结论　乙酰唑胺、高原维康片和红牛饮料均能增强高原机体能量代谢 ,提高机体的有氧运动能力 ,具有良好的抗疲劳作用。Objective To explore the effects of acetazolamide,vitamin tablets, and Redbull drink on human myocardial enzyme after exercises at high altitude. Methods Forty young men living at 3 700 m's altitude for six months were at random divided into four groups, i.e. acetazolamide, vitamin tablets, redbull drink and placebo group, consisting of 10 persons per group. They were asked to pedal the EMG-bicycle ergometer, and the resistance was progressively increased up to exhaustion. Their blood lactic acid (BLA) and ammonia in sera were measured respectively at peaceful hours, before taking drugs, after having taken drugs for 10 days, and 10 days later after stopping the medicine. Results (1) BLA and ammonia in sera were increased in exhaustive exercises (P<0.01). (2) Ammonia and BLA were lower after taking acetazolamide, vitamin tablets and Redbull drink for 10 days (P<0.05 or 0.01). Conclusion Taking acetazolamide and vitamin tablets can reinforce human organism energy metabolism, enhance organism aerobic exercise abillty and have good function of banishing tiredness after exercises at high altitude, and acetazolamide is most effective.

关 键 词：高海拔 药物 渐增负荷运动 血乳酸 血氨 

分 类 号：R594.3[医药卫生—内科学]