华北地区八所医院抗菌药物临床使用干预的研究  

Investigation of intervention with clinical administration of antibiotics at eight military hospitals in North China

作　　者：许景峰[1] 臧晓丽[2] 赵增顺[3] 邢红霞[1] 

机构地区：[1]北京军区总医院药理科,北京100700 [2]北京军区卫生部药材处,北京100042 [3]解放军白求恩国际和平医院普通外科,石家庄050082

出　　处：《华北国防医药》2004年第3期156-159,共4页Medical Journal of Beijing Military Region

摘　　要：目的 :研究和评估“抗菌药物合理应用指导原则”(以下简称“指导原则”)对抗菌药物临床使用干预的适应性、科学性和有效性 ,以及对遏制抗菌药物过度使用和滥用情况产生的作用。方法 :按照“指导原则”和合理用药国际指标 (SDUIs)对抗菌药物的干预指标进行现场调研 ,采集“指导原则”干预前后的住院病人的数据进行自身对照分析。结果 :8家医院的抗菌药使用率 2 0 0 3年较2 0 0 2年平均下降了 19 16% ,预防用抗菌药的使用率下降了 14 2 5 % ,平均用药天数减少了 2 18天。结论 :“指导原则”对抗菌药物的不合理使用干预有效。Objective:Principles & Guidelines for Rational Use of Antibiotics (PGRUA) was implemented in these medical institutions. In this study, its adaptability,rationality and efficiency were assessed. Moreover, its containing effect on overuse and abuse of antibiotics were evaluated.Methods:According to the Principles & Guidelines and Selected Drug Use Indicators(SDUIs), a field survey was performed to collect all data of hospitalized patients before and after implementation of PGRUA. And then a auto-control analysis was carried out.Results:The prescription of antibiotics in the year 2003 was decreased by 19.16% when compared with the year 2002; preventive administration of antiseptics was lowered by 14.25%; the average duration of antiseptic use was shortened by 2.18 days.Conclusions:PGRUA was found effective in intervention with unreasonable use of antiseptics.

关 键 词：抗生素类 药物利用 物质滥用 医院 军队 

分 类 号：R969.3[医药卫生—药理学]