复聪香液治疗血管性痴呆72例临床研究  

Clinical Study on Fucong Xiangye for Treatment of 72 Cases of Vascular Dementia

作　　者：余尚贞 郑国燊 石青 艾立新 陈日荣 

机构地区：[1]广东省江门市五邑中医院,暨南大学第六附属医院内二科,江门市华园东路30号529031

出　　处：《中医杂志》2004年第6期424-425,共2页Journal of Traditional Chinese Medicine

基　　金：江门市科技攻关项目(江科鉴字2003第22号)

摘　　要：目的:探讨复聪香液药氧吸入治疗血管性痴呆的临床疗效及机理。方法:将符合诊断标准的123例患者采用单盲法随机分为治疗组和对照组,观察疗效、红细胞超氧化物歧化酶(SOD)活性、血浆过氧化脂(LPO)、甘油三酯(TG)、血清胆固醇(Tch),高密度脂蛋白(HDL)等项检测指标以及脑电图用药前后的情况。结果:两组患者治疗后症状、评分、所检测指标均有改善,治疗组较对照组明显,两组均无药物不良反应。结论:复聪香液药氧吸入对血管性痴呆有较好的疗效,其机理为使血脂降低、HDL提高以改善动脉硬化,SOD提高,降低LPO含量以清除自由基,抗衰老,抑制脑脂褐质的形成。Objective: To study therapeutic effect and mechanisms of inhalation of drug-oxygen Fuchong Xiangye for treatment of vascular dementia. Methods: 123 cases were randomly divided into treatment group and control group by single-blind. Thertapeutic effects, superoxide dismutase (SOD) activity in red cells, plasma lipid peroxide, triglyceride, serum cholesterol and high density lipid protein (HDL) levels, and electroencephalogram were investigated before and after treatment. Results: The improvement of symptom scores and the above indexes after treatment in the treatment group were more obvious than those in the control group, with no reserve reaction in both groups. Conclusion: Inhalation of drug-oxygen Fuchong Xiangye has a better therapeutic effect on vascular dementia, and the mechanism is related with decrease of blood lipid, and increase of HDL and SOD.

关 键 词：复聪香液 治疗 血管性痴呆 中医药疗法 

分 类 号：R277.7[医药卫生—中医学]