CT测量肾脏皮质厚度与年龄关系的研究  

Relationship between the thickness of the renal cortex and age:study with CT measurement

作　　者：许玉峰[1] 唐光健[1] 

机构地区：[1]北京大学第一医院医学影像科,100034

出　　处：《中华放射学杂志》2004年第8期805-810,共6页Chinese Journal of Radiology

摘　　要：目的 研究肾脏皮质厚度与年龄的关系,确定不同年龄段正常肾脏皮质厚度CT测量的参考范围,筛选出与年龄相关性最好、易于临床应用的测量方法。方法 (1)确定CT测量肾皮质厚度的准确性:选取因肾脏肿瘤而做全肾切除的18例病人的肾脏标本,测量肾脏正常部分的皮质厚度,将测量结果与术前CT影像肾皮质厚度测量的结果行统计学分析,确定差异有无显著性意义;(2)连续选取120例无肾病,无服用肾脏损害药物史,无高血压史病人的腹部CT资料,分为20-40岁、41-60岁、61-80岁3个年龄组,测量每侧肾脏3个层面皮质、实质的厚度和肾脏径线长,统计学分析3个年龄组间差异有无显著性意义及其与年龄的相关性。结果 增强螺旋CT图像测量的肾脏皮质厚度与肾标本测量的皮质厚度差异无显著性意义(t=0.08,P=0.43)。3个年龄组肾脏皮质厚度均数分别为0.73 cm、0.65 cm、0.53 cm,组间差异有极显著性意义(F=93.403,P<0.01)。肾脏皮质、实质厚度与年龄呈负相关,其中相关性最好的指标是皮质厚度(r=-0.78--0.79);60岁以前肾皮质与肾实质厚度比与年龄无相关性。体型对肾脏皮质厚度的影响不明显。男女性别间皮质厚度的差异无显著性意义(P>0.05)。结论 增强螺旋CT能够准确地测量肾脏皮质的厚度,是研究肾脏形态变化的一种敏感的手段。肾皮质厚度随年龄?Objective To study the relationship between the renal cortical thickness and age,and to establish the range of the normal renal cortex thickness by using CT measurement in different age groups so as to obtain a best age-related and practicable method for clinical measurement. Methods (1) the accuracy of measuring renal cortical thickness by CT was evaluated; 18 kidneys resected due to renal neoplasm were studied and the cortical thickness of the normal part of these specimens was assessed. The difference between the renal cortical thickness of specimens and preoperative measurements of renal cortex of the same patient by contrast enhanced CT was analyzed statistically. (2) 120 patients without history of renal disease or long term usage of potentially renal toxic drugs or history of hypertention were examined by CT with indication(s) other than renal disease. All the patients were divided into 20-40, 41-60, and 61-80 year-old groups. The renal cortical and parenchymal thickness and renal size were measured in three CT sections. The difference of the measurements among the three groups and their relationship to age was analyzed statistically. Results There was no significant difference between the renal cortical thickness measured by enhanced spiral CT and measured in renal specimens(t =0. 80,P =0. 43). The renal cortical thickness in three groups was 0. 73 cm, 0. 65 cm, and 0. 53 cm, respectively, and the differences among the three groups were significant ( F = 93.430, P < 0.01 ) .The age and renal cortical and parenchymal thickness was reversely correlated significantly. The renal cortical thickness had the highest correlation with age ( r = -0. 78 - -0. 79 ) . There was no correlation between the age and the ratio of renal cortical thickness and renal parenchyma before 60 years old. The impact of body habitus on renal cortical thickness was not evident. There was no significant differences between the sexes in the thickness of renal cortex(P >0. 05). Conclusion The measurement of the renal cortical thickness w

关 键 词：CT测量 肾脏皮 年龄因素 评价研究 肾脏肿瘤 

分 类 号：R816.7[医药卫生—放射医学]