五倍子水煎剂对124株表皮葡萄球菌(MRSE和MSSE)的体外抗菌活性观察  

Observation of antibacterial activity of wubeizi decoction against 124 strains of staphylococcus epidermidis in vitro

作　　者：岳云升[1] 李仲兴[1] 王秀华[1] 孟晓洁[1] 赵宝珍[1] 陈晶波[1] 李继红[1] 

机构地区：[1]河北医科大学第二医院检验科,050000

出　　处：《河北医药》2004年第9期722-723,共2页Hebei Medical Journal

基　　金：河北省科学技术厅计划内课题 (编号 :0 1 2 76 - 2 1 1 1D)

摘　　要：目的　观察五倍子水煎剂对 12 4株表皮葡萄球菌 (methicillin resistantstaphylococcusepidermi dis ,MRSE和methicillin sensitivitystaphylococcusepidermidis ,MSSE)的体外抗菌活性。方法　采用新的中药抑菌实验方法对五倍子水煎剂进行了体外抗菌活性检测。结果　五倍子对耐甲氧西林的表皮葡萄球菌(MRSE)和甲氧西林敏感表皮葡萄球菌 (MSSE)的抗菌活性均较好 ,其MIC90 均为 0 .2 0 3mg ml( 1∶12 80 ) ,其MIC50 均为 0 .0 5 1mg ml( 1∶10 2 40 )。结论　此项研究为临床治疗由表皮葡萄球菌引起的感染 ,提供了科学依据。Objective To observe the antibacterial activity of Wubeizi decoction against 124 strains of staphylococcus epidermidis (MRSE and MSSE) in vitro.Methods The antibacterial activities of Wubeizi decoction against 124 strains of staphylococcus epidermidis were detected by new test method of TCM bacteriostasis.Results The antibacterial effect of Wubeizi decoction against 124 strains of S.epidermidis was good,and MIC 90 and MIC 50 for 124 strains of S.epidermidis (MRSE and MSSE) were 0.051 mg/ml and 0.203 mg/ml respectively.Conclusion The study results provide scientific basis for clinical treatment of the infection caused by S.epidermidis.

关 键 词：五倍子水煎剂 表皮葡萄球菌 MRSE MSSE 抗菌活性 药物浓度 

分 类 号：R378.11[医药卫生—病原生物学]