肾结石病例对照实验研究  

A CASE-CONTROL STUDY ON RENAL CALCULUS

作　　者：吴礼康[1] 邰昌松[1] 黎松林[1] 陈树培[1] 杨北兵[1] 叶少辉[1] 张朝武[2] 栾荣生[2] 袁萍[2] 

机构地区：[1]深圳市宝安区疾病预防控制中心,深圳518101 [2]四川大学公共卫生学院

出　　处：《现代预防医学》2004年第4期500-502,508,共4页Modern Preventive Medicine

摘　　要：目的 :探讨肾结石与血、尿生化指标的关系。方法 :随机抽取深圳市宝安区 187名肾结石病例和 4 4 7名对照进行病例对照研究 ,采用 t检验、趋势卡方检验等分析血、尿生化指标与肾结石的关系。结果 :血尿素氮病例组高于对照组(t=3.2 0 9,P=0 .0 0 1) ;尿镁 (t=- 1.75 9,P=0 .0 79)、血镁 (t=- 0 .32 9,P=0 .74 2 )病例组低于对照组 ,趋势卡方 (P= 0 .0 0 3)检验显示血尿素氮浓度与肾结石患病危险度成正比。结论 :血尿素氮是肾结石危险因素 ,尿镁、血镁是肾结石的保护因素。Objective:To explore the relation between renal calculus and the biochemistry indexes of blood and urine.Methods:187 renal calculus cases and 447 control cases were selected randomly in Baoan district of Shenzhen city.And case-control study was conducted.The relation between renal calculus and the biochemistry indexes of blood and urine was analysed by t -test and χ 2 -test.Results:The t -test show that the level of carbamide nitrogen of blood in case group is higher than control group( t=3.209,P=0. 001),and the level of magnesium of urine in case group are lower than control group( t=-1.759,P=0.07 9),and the level of magnesium of blood in case group are lower than control group( t=-0.329,P=0 .742).The χ 2 -test shows that the level of carbamide nitrogen of blood is in direct proportion to OR for kidney stone(P=0.003).Conclusion:The carbamide nitrogen of blood is a risk factor of renal calculus,and the magnesium of urine and magnesium of blood are protective factors of renal calculus.

关 键 词：肾结石 实验 尿生化指标 血生化指标 检验 

分 类 号：R692.4[医药卫生—泌尿科学]