环孢素A滴眼液的研制  

Research and preparation of cyclosporine A eyedrops

作　　者：左六一[1] 解新[2] 赵语[1] 王晓江[1] 

机构地区：[1]重庆医科大学临床学院药剂科,重庆400016 [2]重庆医科大学附属口腔医院药剂科,重庆400001

出　　处：《重庆医科大学学报》2004年第5期696-698,共3页Journal of Chongqing Medical University

摘　　要：目的 :建立了环孢素A滴眼液的制备方法。方法 :采用蓖麻油制备环孢素A滴眼液 ,用HLPC测定制剂中环孢素A的含量 ,并对制剂的稳定性进行了考察。结果 :本研究研制的环孢素A滴眼液制备工艺简单 ,质量稳定 ,含量测定快速、准确。结论Objective:To establish the prescription and preparing procedure for the cyclosporine A eyedrops.Methods:The cyclosporine A eyedrops was prepared from castor oil.The cyclosporine A content of the preparation was determined by HPLC,and stability of the preparation was examined,too.Results:The results showed the procedure of preparation was simple,and the quantitative determination was quick,and accurate while the quality was reliable.Conclusion:The procedure described here can be uesed to prepare the cyclosporine A eyedrops.

关 键 词：环孢素A 滴眼液 含量测定 稳定性 

分 类 号：R978.1[医药卫生—药品]