上海市嘉定农村地区糖尿病及其危险因素的流行病学研究  

Epidemiological Study on Diabetes Mellitus and Its Risk Factors in Rural Area in JiaDing Shanghai

作　　者：徐继英[1] 欧阳凤秀[2] 李新建[3] 李锐[3] 戴依群[1] 

机构地区：[1]上海市嘉定区疾病预防控制中心,上海201800 [2]复旦大学医学院流行病学教研室,上海200032 [3]上海市疾病预防控制中心,上海200336

出　　处：《中国慢性病预防与控制》2004年第5期209-212,共4页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：目的探讨上海市嘉定农村地区糖尿病(DM)患病情况及其危险因素,为制订DM防治措施提供依据。方法对2372名上海市嘉定农村地区15岁以上居民的随机抽样人群进行DM流行病学调查,包括问卷调查、体格检查、口服75g葡萄糖耐量试验(75g-OGTT)及空腹血脂等有关生化指标检测,调查人群中DM、糖耐量减低(IGT)和空腹血糖受损(IFG)的患病情况,以及比较它们与正常组之间各指标的差异。并在此基础上以96例DM患者为病例组,2039例糖耐量正常者为对照组,进行病例对-照研究,运用多因素非条件Logistic回归分析,探讨DM可能的危险因素。结果DM、IGT和IFG标准化患病率分别为2.12%,4.01%和3.29%。DM、IGT、IFG与正常组4组间生化指标除高密度脂蛋白(HDL-C)外,各项指标在4组间的差异均有统计学意义。年龄、DM家族史及中心性肥胖为DM发生的危险因素。结论在上海的农村社区人群中,控制体重和代谢综合征是预防和控制糖尿病发生发展的重要措施。Objective To study the prevalence and risk factors of diabetes mellitus (DM),and to provide effective prevention and intervention methods of DM in rural area in Jiading, Shanghai. Methods 2 372 individuals, which were randomly sampled from rural resident population aged more than 15 years in JiaDing Shanghai, were subjected to this epidemiological study of DM. Questionnaire investigation were carried out, and anthropometric parameters, 75 g OGTT, and fasting serum lipids contents were measured. Case-control study was used to study risk factors for DM, and Logistic regression model was introduced. Results The standardized prevalence of diabetes was 2.12%, IGT 4.01%, IFG 3.29%. Except HDL-C, other biochemistrical values were all significantly different among the DM, IGT, IFG, and normal glucose tolerant group. Age, family history of DM, and abdominal obesity were the major risk factors for DM. Conclusions It was important to control the abdominal obesity and the metabolic syndrome, in order to prevent DM in rural area of Shanghai city.

关 键 词：糖尿病 流行病学 患病率 危险因素 

分 类 号：R587.1[医药卫生—内分泌]