三氟甲基磺酸铜(II)手性衍生物:不对称合成中的一类高效催化剂  

Copper(II) Triflate Chiral Derivatives: Versatile Catalysts for Asymmetric Organic Synthesis1

作　　者：李小永[1] 王丽琼[1] 聂进[2] 

机构地区：[1]华中科技大学化学系,武汉430074 [2]曲靖师范学院化学系,曲靖655000

出　　处：《有机化学》2004年第10期1159-1167,共9页Chinese Journal of Organic Chemistry

基　　金：曲靖师范学院科研基金 (No.0 31 390 4 )资助项目

摘　　要：三氟甲基磺酸铜 [Cu(OTf) 2 ]与各种手性磷氮配体络合催化不对称合成已取得了巨大进展 .Copper(II) triflate chiral derivatives chelated with bis(oxazoline)s, phosphoramidites, phosphites, phosphonites or other C 2-symmetric chiral ligands have been extensively studied as excellent chiral catalysts in asymmetric synthesis. This review describes in detail the recent advances in the application of these chiral copper(II) catalysts in enantioselective cycloaddition, aldol, conjugate addition, carbonyl-ene and cyclopropanation reactions.

关 键 词：三氟甲基磺酸铜 不对称合成 手性催化剂 手性双噁唑啉 手性亚磷酸胺酯 手性亚磷酸酚酯 

分 类 号：O643.3[理学—物理化学]