温血高钾持续灌注心肌保护在心脏移植中的应用  

Myocardial Protection by Continuous Perfusion of Warm Oxygenated Blood Plus Potassium in Heart Transplantation

作　　者：李平萍[1] 周庆玲[2] 陈忠堂[2] 孙强[2] 张永善[2] 

机构地区：[1]济宁医学院附属医院,山东济宁272029 [2]山东大学第二医院,山东济南250033

出　　处：《中国体外循环杂志》2004年第2期100-101,共2页Chinese Journal of Extracorporeal Circulation

摘　　要：目的　探讨温氧合血持续灌注对被移植离体心脏保护的临床效果。方法　移植心脏取回后立即行温氧合血高钾 (钾浓度 10～ 2 0mmol/L)持续主动脉根部顺行灌注保护心肌 ,升主动脉开放前停止。结果　 3例移植心脏均自动复跳 ,复苏后心功能良好。结论　温氧合血高钾持续灌注可减少晶体用量 ,缩短供心的缺血时间 ,获得完善的心肌保护效果。OBJECTIVE Objective To study the myocardial protection effect on donor heart by continuous perfusion of warm blood plus potassium .METHODS Continuous perfusion of warm blood plus potassium was initiated immediately after the donor hearts were transferred to the operating room ,and terminated at the aortic cross-clamp release .RESULTS Three transplanted hearts returned to sinus rhythm spontaneously after reperfusion and showed satisfactory cardiac function.CONCLUSION Continuous perfusion of warm oxygenated blood plus potassium can reduce quantity of crystalled used,shorten the time of ischemia,and acquire better myocardial protection effect.

关 键 词：持续灌注 高钾 氧合 心肌保护 温血 移植心脏 心脏移植 复苏后 钾浓度 升主动脉 

分 类 号：R654.2[医药卫生—外科学] R734.2[医药卫生—临床医学]