胎儿胰腺形态及B细胞的免疫组织化学观察  

Immunohistochemical obervation of the morphology and B—cells of the fetal pancreas

作　　者：白经修[1] 付士显 王英华[1] 牛富文 庞静 赵培荣[1] 张林庆[1] 

机构地区：[1]河南医科大学组织胚胎学教研室

出　　处：《河南医科大学学报》1993年第2期118-120,共3页Journal of Henan Medical University

摘　　要：取20例坐高85mm～240mm的胎儿胰腺,按头、体、尾分别取材。组织学观察显示胰腺实质被结缔组织分割成叶或小叶,腺泡分化逐渐清晰,但基底部嗜碱性不明显,提示其外分泌功能还很弱。少量聚集的内分泌细胞与外分泌部细胞无明显界限。仅见较大量聚集成团的内分必细胞外有结缔组织包绕,易与外分泌部区别。免疫组织化学染色显示胰岛内B细胞,各小叶间、叶间B细胞数目差别显著,而同一胰腺的头、体、尾部B细胞数目无明显差异。提示:本研究对临床进行胎儿胰岛移植提供了形态学依据。The pancreatic heads, bodies and tails of 20 aborted fetuses (11～24 weeks)with the sitting heightof 85mm～240mm were fixed in Bouin fluid and embedded in paraffin, and the sections were stainedwith HE and immunohistochemical technique. It was observed that the pancreatic tissue wasdemarcated by the connective tissue to form lobule. With the increase of the gestational age, thedifferentiation of the acini gradually became distinct. The basophilis of acinar base was weak. It wasindicated that the exocrine cellular function was also weak. There was no conspicuous demarcation inthe small number of the accumulated endocrine and the exocrine cells,but there was distinct boundarybetween the large number of the accumulated endocrine cells which were surrounded by the delicateconnective tissue and the exocrine cells. Immunohistochemical stain showed that the distribution of B-cells in the various lobules was variable. And the mumber of the B--cells in the head,the body and thetail of the same pancreas was indistinct. It is suggested that any part of the fetal pancreas may be usedfor the transplantation of pancreas islet.

关 键 词：胎儿 胰腺 胰岛 免疫组织化学 

分 类 号：R321.5[医药卫生—人体解剖和组织胚胎学]