经时型皮肌炎硬皮病重叠综合征1例  

Sclerodermatomyositis: A case Report

作　　者：郑道城[1] 周晖[1] 郭丽君[1] 凌宏忠[1] 卢念祖[1] 佟菊贞[1] 

机构地区：[1]中山大学附属第一医院皮肤科

出　　处：《岭南皮肤性病科杂志》2004年第3期272-274,共3页Southern China Journal of Dermato-Venereology

摘　　要：目的 :报告 1例皮肌炎、硬皮病重叠综合征。患者男性 ,1 4岁 ,反复四肢乏力 5年余 ,左下肢红斑萎缩 2年。肌电图示右肱二头、左股直肌、右三角肌肌源性损害 ;肌活检镜下示肌肉结构基本正常 ,仅见少数肌纤维萎缩 ,间质可见明显炎症病变 ;左下肢皮肤红斑活检镜下示轻度角化过度 ,表皮变薄 ,真皮胶原增厚、增粗 ,附件减少 。Objective:We report a case with sclerodermatomyositis in the paper. Famele case, 14 years old, progressive weakness for 4 years. Erythroma with atrophy on the left leg for 2 years. Electromyogram of right lamb and left leg demonstrated myopathy. The histologic changes were showed thining of epidermis, hydropic degeneration of the basal layer, edema in the papillary dermis, and a perivascular lymphocytic infiltrate in the superficial and deep dermis. The laboratory findings were confirmed the diagnosis of sclerodermatomyositis.[

关 键 词：重叠综合征 皮肌炎 硬皮病 下肢 肌纤维萎缩 间质 皮肤红斑 皮胶原 肌肉 附件 

分 类 号：R593.2[医药卫生—内科学]