冬凌草化学成分的研究  

Chemical Studies on Rabdosia rubenscens

作　　者：刘净[1] 谢韬[1] 魏秀丽[1] 杨菡[1] 杨春华[1] 梁敬钰[1] 

机构地区：[1]中国药科大学天然药物化学教研室,南京210009

出　　处：《中国天然药物》2004年第5期276-279,共4页

摘　　要：目的 :对河南济源产冬凌草的化学成分进行研究。方法 :运用层析手段和波谱方法分离并鉴定了 7个化合物。结果 :它们的结构分别为正三十三烷 (tritriacontane ,1) ,角鲨烯 (squalene ,2 ) ,木栓酮 (friedelin ,3) ,β 谷甾醇 (β sitosterol,4 ) ,N (2 氨甲酰基 苯基 ) 2 羟基苯甲酰胺 5 O β D 阿洛糖苷 (N (2 Aminoformyl phenyl) 2 hydroxybenzamide 5 O β D allopyranoside ,5 ) ,胡萝卜苷 (daucosterol,6 )和 4 乙酰氨基丁酸 (4 acety laminobutanoicacid ,7)。结论 :化合物 5是一个新化合物 ,化合物 1～ 3和AIM:To study the chemical constituents of Rabdosia rubescens [Hemsl.]Hara.METHOD:The chemical constituents were isolated by various chromatographic methods,and the chemical structures were elucidated on the basis of spectral analysis.RESULT:Seven compounds were obtained and their structures were identified as Tritriacontane(1),Squalene(2),Friedelin(3),β sitosterol(4), N (2 Aminoformyl phenyl) 2 hydroxy benzamide 5 O β D allopyranoside(5),daucosterol(6)and 4 Acetylaminobutanoic acid(7).CONCLUSION:Compound 5 is a new compound,and the compounds 1-3 and 7 were isolated from Rabdosia rubescens [Hemsl.]Hara for the first time.

关 键 词：冬凌草 化学成分 新化合物 胡萝卜苷 首次 Β-谷甾醇 糖苷 苯基 角鲨烯 

分 类 号：R284[医药卫生—中药学] R282.71[医药卫生—中医学]