轻度低温治疗27例弥漫性轴索损伤病人的临床疗效  

Clinical effect of mild hypothermia for 27 patients with diffuse axonal injury

作　　者：仪立志[1] 赖连枪[1] 叶宇[1] 贾军[1] 钟天安[1] 周路球[1] 许亦群[1] 尹夕龙[1] 张浚[1] 

机构地区：[1]深圳市龙岗中心医院神经外科,广东深圳518116

出　　处：《中华神经医学杂志》2004年第5期378-379,共2页Chinese Journal of Neuromedicine

摘　　要：目的 探讨早期使用轻度低温治疗中、重型弥漫性轴索损伤(DAI)病人的疗效。方法 对我科收治的27例中、重型弥漫性轴索损伤病人,早期使用冰毯机降温至轻度低温(35℃～35.5℃)脑保护,加用冬眠Ⅰ号等药物配合治疗,但不使用呼吸机和肌松剂。结果 17例存活,10例死亡。存活病人中恢复良好11例,重残6例。结论 该方法适合于基层医院或条件相对不足的医疗单位,仍能取得良好疗效。Objective To discuss the clinical effect of mild hypothermia on the patients with moderate or severe diffuse axonal injury (DAI) in the acute stage. Methods 27 patients with moderate or severe DAI caused by head trauma, whose rectus temperature were maintained at 35℃～35.5℃, were treated with cooling blanket and hibernation drugs but without breathing apparatus and muscle relaxants. Results 11 patients had a good recovery and 6, severe disability; 10 patients died. Conclusion Mild hypothermia with hibernation drugs is an effective means for patients with moderate or severe diffuse axonal injury, especially in the local hospitals with poor medical conditions.

关 键 词：病人 轻度低温 弥漫性轴索损伤 治疗 重型 早期 临床疗效 冬眠 存活 恢复 

分 类 号：R651[医药卫生—外科学] R743[医药卫生—临床医学]