支气管哮喘患儿血清SOD、ET和NO水平检测的临床意义  

Clinical significance of serum SOD,ET and NO levels in children with bronchial asthma

作　　者：高长龙[1] 

机构地区：[1]江苏省连云港市第一人民医院儿科,222002

出　　处：《淮海医药》2004年第6期457-458,共2页Journal of Huaihai Medicine

摘　　要：目的　探讨支气管哮喘患儿血清超歧过氧化物酶 (SOD)、内皮素 (ET)和一氧化氮 (NO)水平的变化。方法　分别应用放免法和化学法检测 36例支气管哮喘患儿血清 SOD、ET和 NO水平 ,并与 35例正常健康儿作比较。结果　支气管哮喘患儿血清 SOD水平显著低于正常儿 (P<0 .0 1 ) ,而 ET、NO水平则明显地高于正常儿童 (P<0 .0 1 )。结论　血清 SOD、ET、NO参与了支气管哮喘的发病过程 。Objective To study the changes of serum super-oxidate dismatase(SOD),endothelal(ET) and nitric oxide(NO) levels in children with bronchial asthma.Methods Serum SOD and ET levels were determined by RIA,and NO level by chemistry in 36 children with bronchial asthma and 35 normal controls.Results Serum ET and NO levels in bronchial asthma children were significantly higher than those in normal controls( P <0.01),while SOD level decreased( P <0.01).Conclusion Serum ET,NO and SOD might play an important role in bronchial asthma children recovery and be closely related to the mechanism of bronchial asthma children.

关 键 词：支气管哮喘 血清SOD ET NO水平 患儿 正常儿童 临床意义 

分 类 号：R562.25[医药卫生—呼吸系统] R971.8[医药卫生—内科学]