糖尿病家族史对老年Ⅱ型糖尿病并发症的影响  

EFFECT OF DIABETIC FAMILY HISTORY ON DIABETIC COMPLICATIONS

作　　者：吴素芬[1] 尤传一[1] 孙皎[1] 唐尧[2] 

机构地区：[1]华东医院内分泌科,上海市200040 [2]南京铁道医学院附院内分泌科

出　　处：《老年医学与保健》1999年第1期32-34,共3页Geriatrics & Health Care

摘　　要：目的 探讨Ⅱ型糖尿病遗传因素对并发症的影响.方法 Ⅱ型糖尿病人501例,其中男性219例,女性282例.由专科医师根据临床及实验室检查,诊断糖尿病并发症,按有无糖尿病家族史分组,并作ι检验.结果 有家族史的糖尿病患者,并发周围神经病变、冠心病、脑血管病和白内障,明显多于无家族史的糖尿病者.大于60岁的老年人,有糖尿病家族史的男性糖尿病患者,其周围神经病变、脑血管病和白内障的发病率明显高于无家族史的男性糖尿病相应并发症.在女性仅周围神经病变发生率明显增多.结论 遗传因素在糖尿病并发症发病中具有重要意义.Objective Investigating the effect of type Ⅱ diabetic genetic factor on diabetic complications. Methods 501 cases of type Ⅱ diabetes (219 males, 282 females) with or without complications were diagnosed by specialists by means of clinical and laboratory examinations. Statistical analysis was done by t test. Results The complications of peripheral neuropathy, coronary heart disease, cerebrovascular disease and cataract in diabetes patients with family history were statistically higher than those without family history. In over 60 elders, the incidences of peripheral neuropathy, cerebrovascular disease and cataract in males with family history were apparently higher than those without family history, while only the incidence of peripheral neuropathy was apparently higher in females with family history. Conclusions Genetic factors play an important role in diabetic complications.

关 键 词：糖尿病并发症 糖尿病家族史 周围神经病变 男性 老年Ⅱ型糖尿病 白内障 糖尿病患者 

分 类 号：R587[医药卫生—内分泌] R363.2[医药卫生—内科学]