危重病患者甲状腺激素水平与预后的关系  

Relationship between acute physiology and chronic health evaluation and levels of thyroid hormone in serious patients

作　　者：谢健敏[1] 洗汉海 邓勇强[1] 

机构地区：[1]佛山市顺德区第一人民医院检验科,广东佛山828300 [2]佛山市顺德区第一人民医院内科,广东佛山828300

出　　处：《中国基层医药》2004年第9期1035-1036,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　探讨危重病 (ICU)患者甲状腺激素水平与急性生理学与慢性健康状况评分 (APACHE)关系。方法　用放免法测定 12 0例ICU患者的甲状腺激素水平并与疾病严重程度进行比较。结果　A PACHE评分越高 ,TT3 、TT4含量下降越明显 ;APACHE评分与TT3 、FT3 含量均呈负相关 (r1=- 0 5 0 6 ,r2= - 0 4 34,P均 <0 0 5 ) ;各组TT3 和FT3 含量均低于对照组 (P <0 0 5～ 0 0 1) ;治疗后TT3 、FT3 含量高于治疗前 (P <0 0 5 ) ;死亡组TT3 和FT3 的含量明显低于存活组 (P <0 0 5 )。结论　危重病患者病情越重 ,甲状腺激素水平下降幅度越大 ;TT3 和FT3Objective To examine the relationship between the acute physiology and chronic health evaluation(APACHE Ⅲ) score and levels of thyroid hormone.Methods APACHE score was derived as deseribed and the content of thyroid hormone was measured by radioimmunoassy(RIA) in 120 patients with ICU.Results The higher the APACHE score,the more the decreases in the content of triiodothyronine(TT_3) and free triiodothyronine(FT_3).The content of TT_3 and FT_3 was negatively related to APACHE Ⅲ score(r_1=-0.506,r_2=-0.434,P<0.05).The content of TT_3 and FT_3 were obviously lower in the study group than in the control group(P<0.05～0.01) and lower in the death group than in the surrival group(P<0.05).Conclusion The content of TT_3 and FT_3 can predict the prognosis of ICU patients.

关 键 词：TT3 FT3 甲状腺激素水平 含量 危重病患者 预后 评分 

分 类 号：R449[医药卫生—诊断学]