肝纤维化指标在甲亢病中应用的探讨  

Study on the Application of Hepatofibrosis Index in Hyperthyroidism

作　　者：朱诚忆[1] 付鸿叶[1] 石根明[1] 吴健媛 

机构地区：[1]浙江大学医学院附属第一医院核医学科,浙江杭州310003 [2]浙江义乌市人民医院核医学科,浙江义乌321000

出　　处：《标记免疫分析与临床》2004年第3期135-137,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：探讨肝纤维化指标在甲亢中的应用。对照组 5 5名 (男 2 9名 ,女 2 6名 ) ;甲亢组为经13 1I治疗ATD治疗后患者共 173例 (男 5 8例 ,女 115例 ) ,用RIA测定甲状腺功能及肝纤维化指标。结果提示 ,甲亢患者血清PCⅢ、Ⅳ·C水平显著增高 ,并与TT3 、TT4、FT3 和FT4的增高一致 ;血清PCⅢ、Ⅳ·C水平与甲状腺肿大呈明显正相关 ;甲亢患者PCⅢ、Ⅳ·C阳性率 (% )与甲状腺功能指标的阳性率 (% )相符。本文认为PCⅢ、Ⅳ·C可作为甲亢的诊断和疗效观察新的辅助指标之一。To explore the changes of hepatofibrosis index in hyperthyroidism, the index of thyroid function and hepatofibrosis were assayed by RIA in 173 patients with hyperthyroidism and 55 normal persons.The results showed that the levels of PCⅢ,Ⅳ·C and HA were significantly higher than that of normal control.Furthermore, these serum levels of hepatofibrosis were concordance with that of TT 3,TT 4,FT 3 and FT 4 in hyperthyroidism.The serum levels of PCⅢ,Ⅳ·C were positive correlated with that of goiter.The positive rate of PCⅢ and Ⅳ·C in hyperthyroidism is conformed with that of the index of thyroid function.The study suggested that PCⅢ and Ⅳ·C may be a new supplementary index of the diagnosis and observation of curative effect in hyperthyroidsim.

关 键 词：甲亢患者 肝纤维化指标 Ⅳ-C PCⅢ 甲状腺功能 血清 诊断 水平 高一 提示 

分 类 号：R581.1[医药卫生—内分泌] R575[医药卫生—内科学]