丹参黄芪注射液的药理实验研究  

THE PHARMACOLOGICAL EXPERIMENTAL STUDY ON “RED SAGE ROOT” AND “AST RAGALUS ROOT” INJECTION

作　　者：李月雄[1] 白秀玉 韩志君[1] 冯承善[1] 张佩珍 刘英[1] 石浴非 

机构地区：[1]黑龙江省医院

出　　处：《黑龙江中医药》1993年第2期36-38,共3页Heilongjiang Journal of Traditional Chinese Medicine

摘　　要：丹参,黄芪注射液是由丹参,黄芪等药组成,临床上用于治疗冠心病之心绞痛、心肌梗塞、脑血栓及其后遗症、脑供血不足等。为了探讨该制剂对心、脑血管疾病的药理作用,确保临床用药的安全和有效,特进行药理实验,结果表明:丹参黄芪注射液有极显著的耐缺氧作用(P<0.01),其存活时间延长百分率为99.05%,约为对照组的两倍,L_(D50S)=61.93±5.8g/kg,无毒、无刺激性、无渗血及凝血现象,过敏试验及热原检查均合格,为临床应用提供了科学依据。“Red sage root”and“astragalus root”injection was mainly composed of“red sage root”and“ast(?)agalus root”to treat anginapectoris (coronary heart disease),myocardiac infarction,cerebral thrombosis and its sequel,In order to approch the pharmacological effects of thisinjection on angiocardiapathy and cerebrovascular diseases ensure the clinical application,we did this experiment.The results shown that“red sage root”and“astragalus root”injectionhad obvious hypoxiastabile,(P<0.01)the percentage of prolonging the life-time was 99.05percent,it was about two times of the controlled group's LD50=61.93±5.89g/kg,non--stimulation,non-hemolysis and non-coagulation,allergic reaction and pyrogen test werequlified,these provided the scientific basis for clinical application.

关 键 词：丹参 黄芪 药理学 

分 类 号：R285.5[医药卫生—中药学]