鼻咽组织光热响应研究  

Study on the Optical-thermal Response of Nasopharyngeal Tissue

作　　者：沈桂平[1] 谢树森[2] 李晖[2] 陈珍黎[3] 

机构地区：[1]厦门大学物理与机电工程学院,福建厦门361005 [2]福建师范大学物理光电信息科学院,福建福州350007 [3]福建省同安第一中学,福建厦门361100

出　　处：《光电子．激光》2004年第10期1255-1259,1262,共6页Journal of Optoelectronics·Laser

基　　金：国家自然科学基金资助项目(60178022);福建省自然科学基金重大资助项目(2002F008)

摘　　要：利用生物传热理论模型Pennes方程对Ar+激光辐照下生物组织的温度分布进行模拟研究;实验测定了离体猪鼻咽组织在Ar+激光(λ=488.0nm和514.5nm)辐照下不同位置的温度分布,重点研究了辐照功率密度和波长对组织中温度分布的影响。理论和实验结果表明:组织中的温度分布与组织不同深部位置、激光波长以及激光辐照功率密度有关;实验获得波长488nm和514.5nm的Ar+激光分别辐照鼻咽组织时安全光剂量分别为1.85W/cm2和1.72W/cm2。The temperature distribution in nasopharynx tissue induced under the irradiation of rgon ion laser emitting at the wavelength of 488.0 nm and 514.5 nm were simulated by Pennes bioheat transfer equation.Furthermore,the dependence of measuring position,irradiation time and irradiation energy density,as well as wavelength on the temperature distribution was studied in detail.Simulation results and experimental results show that the temperature distributions in the porcine nasopharynx tissue were significantly affected by measuring position and the energy density and wavelength of irradiation laser.The safe dose of porcine nasopharynx tissue during the irradiation of argon ion laser at the wavelength of 488.0 nm and 514.5 nm is 1.85 W/cm^2 and 1.72 W/cm^2,respectively.

关 键 词：鼻咽组织 Ar^+激光 光热 离体 激光辐照 光剂量 部位 功率密度 激光波长 温度分布 

分 类 号：TN248[电子电信—物理电子学] R318.51[医药卫生—生物医学工程]