降钙素原和C-反应蛋白对脓毒症的诊断价值比较  

Comparison of Procalcitonin(PCT) and C-Reactive Protein as Diagnostic Markers of Sepsis

作　　者：时兢[1] 宋秀琴[2] 俞亚芬[2] 穆会君[1] 

机构地区：[1]南京医科大学附属无锡市第一人民医院ICU,无锡214002 [2]苏州大学附属无锡市第四人民医院ICU

出　　处：《临床急诊杂志》2004年第5期7-8,共2页Journal of Clinical Emergency

摘　　要：目的:比较血清降钙素原(PC7)和C-反应蛋白(CRP)对脓毒症的诊断价值。方法:以最终临床诊断为金标准,计算以不同浓度作为截断点时PCT和CRP的灵敏度、特异性及尤登指数。结果:PCT的特异性和诊断准确性高于CRP,其灵敏度较CRP低。结论:PCT测定诊断脓毒症的较好指标。Objective:To compare the value of serum procalcitonin (PCT) and C-Reactive protein (CRP) in diagnosis of sepsis. Methods:The sensitivity and specificity and Youden index were calculated according to different levels of cutoff score.in response to the final clinical diagnosis as golden standard. Results: PCT had a higher specificity and accuracy than CRP, but lower sensitivity. Conclusion : PCT routinely measurements could be used as an effectie diagnostic marker of sepsis. PCT is a better marker of sepsis than CRP.

关 键 词：CRP 脓毒症 PCT 诊断价值 C-反应蛋白 血清降钙素原 特异性 金标准 临床诊断 诊断准确性 

分 类 号：R631[医药卫生—外科学] R541.4[医药卫生—临床医学]