先天性TORCH感染与头颅CT对照的临床分析  

Clinical analysis of head CT and congenital TORCH infections

作　　者：韩虹[1] 杨辉[1] 夏丽[1] 

机构地区：[1]山西省儿童医院,030013

出　　处：《中国优生与遗传杂志》2004年第5期125-125,126,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的　分析先天性TORCH感染与头颅CT的临床改变。方法　CT扫描采用西门子SomatomDKL型或Smil型CT机 ,层厚层距均为 8mm ,从OM线至颅顶连续扫描。病原学采用TORCH -IgM四联筛检试剂盒检测。结果　头颅CT显示所有病人均有钙化 ,脑发育不良 8例 ,脑室扩大 10例 ,异常脑裂 6例 ,脑穿通畸形 4例 ,平滑脑 2例。实验室检查 ,巨细胞病毒感染 11例 ,疱疹病毒感染 4例 ,风疹病毒感染 3例 ,弓形虫感染 2例。结论　TORCH感染对儿童神经系统的损害是严重的 ,当婴幼儿头颅CT有异常发现时 ,应尽早进行血清病原学的检查 。Objective: To investigate the clinical and neuroimaging changes of congenital TORCH infections. Methods: Using head computed tomography (CT, type Somatom DRI or Smil of SEMENS) scan to detect the brain structure abnormalities. Diagnosis of infectious etiology is confirmed by identification of species-specific immunoglobulin M. Results: CT scan of brain revealed intracranial calcification in all patients, encephalic hypoplasia in 8 cases, dilated ventricles in 10 cases, schizencephaly in 6 cases, hydrencephaly in 4 cases and smoth brain in 2 cases. Serologic tests showed cytomegalovirus infection in 11 cases, herpes simplex virus infection in 4 cases, rubella in 3 cases and toxoplasmosis in 2 cases. Conclusion: Our findings indicated that injury of central nervous system(CNS) following TORCH infections was severe. Serologic tests should be performed early when CT scan of brain appeared abnormal and treatment should be done in time.

关 键 词：TORCH感染 头颅CT 儿童 临床 

分 类 号：R725.1[医药卫生—儿科]