Norplant皮下埋植者淋巴细胞姐妹染色单体交换频率的观察  

Study of the Effect of Norplant on Lymphocytes Sister Chronatid Exchange Frequency and Chromosome Abnormality

作　　者：柯致和 王佩珠[2] 黄贻凤[1] 解梦霞[1] 涂知明[1] 庞美玲[3] 

机构地区：[1]湖北医学院生物教研室 [2]湖北医学院附属第二医院妇产科 [3]湖北医学院附属第二医院

出　　处：《湖北医学院学报》1993年第1期30-31,共2页

摘　　要：从细胞遗传学角度观察 Norplant 对女性皮下埋植者淋巴细胞姐妹染色单体互换(SCE)率的影响观察组27人,Norplant 埋植时间五年,对照组为6名健康女献血员.结果:观察组及对照组SCE 频率((?)±S)分别为9.80±2.33,9.05±3.81两组比较.差异无显著性(P>0.05),提示 Nor-plant 未引起妇女的遗传物质损伤,此项皮下埋植术的避孕方法适合中国妇女使用。27 women used Norplant for 5 years as a experiment group and 7 persons without Norplant as a control group were studied.The frequencies of sister chromatid exchange between the experiment group (9.8±2.33) and the control group (9.05±3.81) differed no significantly (P>0.05).The results suggested that Norplant can not cause the chromosome obvious damages and may be used as a good contraceptive for married women who want to get conceived later.

关 键 词：避孕药 染色体 生理学 

分 类 号：R979.21[医药卫生—药品]