瘦素与充血性心力衰竭  

Leptin and Congestive Heart Failure

作　　者：张金国[1] 杨娜[2] 王学忠[2] 宋光耀[2] 

机构地区：[1]济宁医学院附属医院心内科,山东济宁272029 [2]河北省人民医院心脏中心,河北石家庄050051

出　　处：《心血管病学进展》2004年第5期370-373,共4页Advances in Cardiovascular Diseases

摘　　要：瘦素是与肥胖密切相关的内分泌激素 ,但目前对瘦素的研究已超越肥胖的范畴 ;许多研究表明 ,瘦素与心血管疾病关系密切 ,而且可能参与了充血性心力衰竭分解代谢等病理生理过程。Leptin,a multipeptide hormone produced by adipose tissue,is known to induce anorexia,increase energy expenditure and induce weight loss.As plasma leptin levels were elevated in patients with congestive heart failure(CHF),it has been conjectured that leptin may play a role in catabolic pathophysiology of CHF.

关 键 词：瘦素 充血性心力衰竭 肥胖 内分泌激素 心血管疾病 病理生理过程 分解代谢 

分 类 号：R541.6[医药卫生—心血管疾病]