肝病患者革兰阴性细菌感染的临床分析  

G^- Bacteria Infection in Patients with Hepatic Disease

作　　者：张文中[1] 郭秋艳[1] 刘海霞[1] 

机构地区：[1]首都医科大学附属北京佑安医院感染科

出　　处：《首都医科大学学报》2004年第3期341-344,共4页Journal of Capital Medical University

摘　　要：从肝病患者的体液及血液中分离、鉴定革兰阴性细菌菌株 ,同时测定革兰阴性细菌产超广谱 β 内酰胺酶率及对抗生素的耐药情况 ,以了解细菌感染的分布 ,为临床合理用药提供依据。结果 :肝病患者革兰阴性病原菌以大肠杆菌、肺炎克雷伯菌和气单胞菌属占多数。产酶株主要分布在肺炎克雷伯菌和大肠杆菌 ,其敏感性低于非产酶株。提示To investigate the spectrum of bacteria isolated from hepatitis and characteristics of drug resistance and to evaluate the clinical preventive and therapeutic measures, the bacterial spectrum separated from blood/body fluids of patient with hepatitis were examined to estimate the ability of producing enzyme. And their drug resistance and clinical characteristics were analysed. Result of the G - bacteria, Escherichia coli, Klebsiella pneumoniae and aeromonas strains were the major ones. The bacteria producing beta-lactamase were mainly from Escherichia coli and Klebsiella pneumoniae and their susceptibilities to antibiotic were lower than those of no enzyme product bacteria. The result indicates that antibiotics should be selected based on susceptibility.

关 键 词：肝病患者 革兰阴性细菌 产酶株 肺炎克雷伯菌 临床分析 感染 抗生素 大肠杆菌 菌株 体液 

分 类 号：R446.5[医药卫生—诊断学] R364.5[医药卫生—临床医学]