新型水溶性壳聚糖衍生物的制备  

Preparation of a New Water-soluble Derivatives of Chitosan

作　　者：齐从丽[1] 马喜平[1] 

机构地区：[1]西南石油学院化工学院,四川成都610500

出　　处：《化工时刊》2004年第9期42-43,共2页Chemical Industry Times

摘　　要：以醋酸和丙酮为反应介质 ,利用马来酸酐在均相条件下对壳聚糖进行水溶性N -酰化改性 ;与壳聚糖相比 ,改性后的壳聚糖衍生物的水溶性有了很大改善。实验表明 :对壳聚糖的N -酰化改性程度越高 ,其改性产物的水溶性越好 ;同时 ,制备的 3种样品的产率均在 90 %以上。Some N-acylating chitosan derivatives were synthesized through the reaction of malic anhydride and chitosan in the presence of acetic acid and acetone in homogeneous solution.In contract to the original chitosan,the water-solubility of these derivatives was much improved.The experiment showed that with the increase in the degree of N-acylation of chitosan,the water-solubility of products are greatly improved.Moreover,the productivities of those three productions were all over 90%.

关 键 词：N-酰化 改性产物 水溶性壳聚糖 新型 制备 马来酸酐 壳聚糖衍生物 丙酮 反应介质 产率 

分 类 号：TQ28[化学工程—有机化工]