P物质抑制剂在增生性疤痕中的应用  

Substance P restraining drug injecting therapeutics to treat the hyperplasic scar

作　　者：朱小波[1] 宋朝骏[1] 袁启智[2] 黄硕麟[2] 陈玉林[3] 

机构地区：[1]上海市第七人民医院烧伤疤痕手功能治疗中心,上海200137 [2]上海市第一人民医院,上海200080 [3]上海市长海医院,上海200433

出　　处：《上海预防医学》2000年第7期324-326,共3页Shanghai Journal of Preventive Medicine

基　　金：上海市领先学科特色专科课题

摘　　要：了解P物质抑制剂在治疗增生性疤痕中的疗效。 [方法 ]　从 1998年到 2 0 0 0年 6月应用传统注射激素疗法治疗增生性疤痕患者 178例 ,同期运用注射P物质抑制剂治疗增生性疤痕患者 137例 ,进行疗效比较。[结果 ]　接受P物质抑制剂治疗的患者 ,疤痕评分平均下降 34 % ,运用传统激素治疗方法的患者治疗前后平均评分下降 2 3% ,且运用P物质抑制剂治疗的复发率为 18 7% ,传统的激素注射疗法治疗复发率为 76 5 %。 [结论 ]　在治疗增生性疤痕时应首选P物质抑制剂。Objective] To compare the curative effect of the traditional injecting bormonal drug and substance P restraining drug injecting therapeutics to treat the hyperplastic scar.[Method] using traditional injecting therapeutics to treat 178 cases of sufferers and substance P restraining drug to treat 137 cases of sufferers with injecting therapeutics from 1998 to June 2000.[Result] following one year, we found the grade of the sufferers of accepting substance P restraining drug decreased 34%.The grade of the sufferers who accepting traditional hormonal treatment decreased 23%. Using substance P restraining drug injecting the recrudescent rate was 18.7%. Using traditional injecting therapeutics the recrudescent rate was 76.5%.[Conclusion] we shall choose substance p restraining drug when we are treating the hyperplastic scar with the injecting therapeutics

关 键 词：治疗 P物质 增生性疤痕 患者 抑制剂 复发率 激素注射 应用 下降 激素疗法 

分 类 号：R619.6[医药卫生—外科学]