骨髓间质干细胞在缺血性心脏病中的应用  

Application of mesenchymal stem cells in ischemic heart diseases

作　　者：安英华[1] 张建军[1] 

机构地区：[1]上海市交通大学附属第一人民医院心内科,上海200080

出　　处：《中国心血管杂志》2004年第5期376-378,共3页Chinese Journal of Cardiovascular Medicine

摘　　要：骨髓间质干细胞(MSCs)是一种多能造血于细胞,在一定诱导条件下,可分化为多种造血外组织细胞,如骨细胞、软骨细胞、 心肌细胞等,因此,在组织工程方面具有广泛的应用前景。近年来,MSCs在缺血性心脏病中的应用价值已得到证实和肯定,从而为 缺血性心脏病的治疗带来了新的契机。本文就骨髓间质干细胞在缺血性心脏病中的应用进行了回顾和展望。Mesenchymal stem ceJls(MSCs) is a kind of multipotent stem cells, which have the capacity to differentiate into many kinds of cells, such as osteocytes, chondrocytes, cardiomyocytes , and so on. So MSCs has a broad foreground in tissue engineering application, During recent years, the value of MSCs in ischemic heart diseases application has been validated and confirmed, which may bring new chances for the treatment of ischemic heart diseases. This article makes a review and expectation concerning the application of MSCs in ischemic heart diseases.

关 键 词：缺血性心脏病 骨髓间质干细胞 治疗 软骨细胞 造血干细胞 心肌细胞 组织工程 诱导条件 分化 MSC 

分 类 号：R541[医药卫生—心血管疾病] R329[医药卫生—内科学]